News for hackers. Stuff that matters.
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by TomGullen on Monday November 09, 2020 @07:08AM (#25033901)
Great news and the markets are reacting very positively to the news as well which indicates to me this could be the beginning of the end!
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by andrepd on Monday November 09, 2020 @08:07AM (#25034369)
The markets? Spare me. What are the markets, a handful of rich in banks and large corporations? They are neither wise nor competent, why should every news story be suffixed by how "the markets" (swt) react?
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by pembrook on Monday November 09, 2020 @12:44PM (#25037330)
> What are the markets, a handful of rich in banks and large corporations?

Glad you asked. No, "the markets" are not simply a handful of rich people, banks and large corporations. The markets are also more than just "stocks."

In fact, the majority of "the markets" is actually bonds, and most of those bonds are debt issued by nearly all the countries of the world (sovereign bonds). I think roughly 80 Trillion dollars, but don't quote me.

If you live in a country with roads, infrastructure, buildings, etc.--then the markets are responsible for everything around you.

But you seem to be complaining about stocks since they get the most media attention, so let's look at those.

You may not realize it, but the future of every single country with a socialized pension system, sovereign wealth fund, etc. depends on the returns of global stocks. They make up only a portion of most pension portfolios, but deliver nearly all of the returns. Everybody has a stake in them even if they don't realize it.

Are the markets all-knowing or perfectly efficient? Of course not. But it's literally the only place where you can measure how a global herd of humans are feeling about the state of the world at any given time with a single number. This makes it a default reference for journalists to cite, ie. "thing happened, this is what the humans and their algorithms collectively think about it."

The journalists are often wrong and don't understand what's happening, but this case seems to be pretty straightforward.

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by andrepd on Monday November 09, 2020 @07:24PM (#25041610)
>If you live in a country with roads, infrastructure, buildings, etc.--then the markets are responsible for everything around you.

See, this kind of thing really gets to me. Here's you circa 1290: "If you live in a fiefdom with wells, irrigation, castles, etc. -- then your Lord is responsible for everything around you." See how fallacious that sounds when you transpose it this way?

The central issue is that you're justifying a thing from the context of the thing itself. You're explaining modern capitalism from the framework of modern capitalism. It's circular, and you get ridiculous things like "the markets built the roads". Ahm, no, workers built the roads!

>Are the markets all-knowing or perfectly efficient? Of course not. But it's literally the only place where you can measure how a global herd of humans are feeling about the state of the world at any given time with a single number.

They are a weighted way of seeing how some humans are feeling about things. A number that gives as much weight to 8 guys as it does to 3.7 billion. It's a pretty shitty indicator, I'd say.

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by pembrook on Tuesday November 10, 2020 @02:13AM (#25043493)
> "your Lord is responsible for everything around you." See how fallacious that sounds...?"

Of course it sounds fallacious--you've constructed a straw man out of my original argument.

There's nothing circular about the concept of debt. It's a fundamental aspect of how our economy works. The way debt is raised is through markets. Again, this is not a controversial or political statement.

Of course workers built the roads. And they were paid to build those roads by debt raised via bond markets. Governments and organizations use debt to bring the future into the present and amortize large investments over long periods of time. The liquidity and demand for this debt in the global markets allows them to do this.

No marketplace for debt = no way to reliably execute big infrastructure projects for all but the richest of countries. The market (the demand for debt) is literally the enabler.

Nothing I've said here is a mischaracterization of reality.

> It's a pretty shitty indicator, I'd say.

Again, I'm not advocating that short term financial market gyrations have any explanatory power for the future. I'm simply explaining why journalists use it: because it's easy.

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by jdhzzz on Monday November 09, 2020 @08:35AM (#25034620)
> What are the markets, a handful of rich

I'm not yet but hoping to be...

> They are neither wise nor competent

That's me again, but doesn't preclude my success...

However this 1995 paper (1) indicates that the S&P 500 behavior does "Granger Cause" changes in USA GDP. i.e changes in S&P 500 does predict changes in GDP from 1 to 3 quarters out. So that's the one legitimate reason to be encouraged by rising markets. Perhaps the woman who cuts my hair will be able to get off food stamps by spring.

1. https://digitalcommons.iwu.edu/cgi/viewcontent.cgi?redir=1&a...

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by ploika on Monday November 09, 2020 @08:44AM (#25034702)
Since you asked, also the pension funds of almost everyone you know.
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by zzbzq on Monday November 09, 2020 @10:08AM (#25035509)
retirement accounts--pensions are legacy technology
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by bluGill on Monday November 09, 2020 @01:55PM (#25038244)
Which is too bad. I'd rather have a pension and be assured of my income for however long I live than have to figure out how much to leave in my account for a future that I might not live to be old enough to enjoy.
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by chasd00 on Monday November 09, 2020 @09:59AM (#25035427)
and 401ks
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by Beached on Monday November 09, 2020 @11:00AM (#25036126)
do you not have a 401k or ira or other similar fund?
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by ECA_stax on Monday November 09, 2020 @04:21PM (#25040073)
What did you mean by swt? Surely you are not making fun of Islam in a completely unrelated thread.
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by andrepd on Monday November 09, 2020 @07:18PM (#25041566)
Obviously, I'm ironically sanctifying the term "The Market" as a rhetorical device. Replace "swt" with "hallowed be His name" if you prefer.
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by coryfklein on Monday November 09, 2020 @12:33PM (#25037223)
Are you suggesting that the signal of the markets today has zero corellation with the promise of this vaccine? That seems like quite the position to take.

Or are you lamenting that much attention is given to something that is primarily driven by wealthy organizations? I guess I might sympathize with you there.

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by TomGullen on Monday November 09, 2020 @08:51AM (#25034770)
I'm not a vaccine expert, so when vaccine news comes out and the broader market reacts extremely positively to this news it just gives me confidence this is the real deal.

There has been other vaccine news in the past which my friends/family talk about excitedly but the broader market didn't budge much.

I don't see any problem in using it a general barometer for this sort of news.

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by aphextron on Monday November 09, 2020 @09:00AM (#25034862)
>Great news and the markets are reacting very positively to the news as well which indicates to me this could be the beginning of the end!

I'd argue that has a lot more to do with the election uncertainty being over with. This is incredibly promising news, but probably not enough to account for SP500 jumping 400 points this morning.

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by 0xffff2 on Monday November 09, 2020 @10:52AM (#25035990)
S&P 500 is only up 90 points right now, and I don't see any evidence it was up 400 at any point today.

More generally, The DOW is way up, S&P up moderately, and NASDAQ only up a little bit. That looks like it may well be a result of vaccine news to me, which is less good for the big tech companies that make up the NASDAQ than the broader set of companies tracked by the DOW and S&P. I would expect an election related bump to have pretty equal effects on all three indices.

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by skhm on Monday November 09, 2020 @07:53AM (#25034227)
There is another quite negative reading of this comment and I'm not sure which one you meant :)
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by coldpie on Monday November 09, 2020 @08:00AM (#25034289)
Yeah, setting aside all the politics and silliness, the science going on around this pandemic is remarkable. Going from nearly zero (yes, there was a bunch of research from SARS-Cov-1, MERS, and similar to build off of but nothing like this) to a functioning, tested, and mass manufactured vaccine in a year is absolutely jaw dropping. Even if it takes two years to distribute widely, three years to stomp out a pandemic is blindingly fast and a major credit to modern medical science, and the processes we have built up around it.
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by bipson on Monday November 09, 2020 @08:06AM (#25034351)
Although I want to agree, none of the companies started from zero.

All these new technologies, the techniques, the principles were in development since years if not decades.

Not trying to diminish the accomplishments achieved, great effort nontheless. Just saying nobody started from zero here, that would have been insane and frankly impossible.

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by lbeltrame on Monday November 09, 2020 @08:23AM (#25034494)
> All these new technologies, the techniques, the principles were in development since years if not decades.

Yes, I first heard about intramuscular nucleic acid injection around the year 2000. At the time it was naked DNA and not RNA in a lipid nanoparticle suspension, but the principle was the same.

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by bipson on Monday November 09, 2020 @08:39AM (#25034661)
In particular BioNTech from the article was founded 2008. This is their first publicly available "product" - it applies their vision for cancer treatment to specific SARS-nCoV-2 proteins (arguably I don't know if they're working on other ideas as well).

They might be working on this particular vaccine since 2020, but AFAIK they have been working on the specific principle the vaccine uses since 2008.

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by usrusr on Monday November 09, 2020 @08:43AM (#25034691)
True, but it's the first time we see those technologies in action. Some (many?) of the vaccine projects for example use paths that have previously been considered, played through in "toy" projects that never made it to production and so on, and now they are suddenly standing in the limelight, going live. For some sub-fields of biotech this must almost be like the mindboggling aviation had from roadshow curiosities to a major war factor in hardly more than a decade.
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by thinkharderdev on Monday November 09, 2020 @08:46AM (#25034723)
I don't really understand the underlying science but the nucleic acid based vaccine platforms seem really, really exciting. Getting an effective COVID vaccine is obviously huge, but the ability to rapidly develop vaccines in the future for emerging pandemics is amazing.
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by ApolloFortyNine on Monday November 09, 2020 @02:02PM (#25038343)
What I find more impressive is Moderna was finalized in February, and most of the other candidates were finalized by March.

If we could somehow develop rapid testing in some way, it's shocking to me that the vaccine could have entered mass production by the Summer.

There was a time where the only true way to test a new model Aircraft was to build one, but nowadays pretty much every characteristic is well understood by the time it enters service. To reach a similar point with vaccine testing will be important when the next pandemic hits.

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by easytiger on Monday November 09, 2020 @10:01AM (#25035453)
DNA/RNA vaccinations have been around for 30 years or so.
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by cblconfederate on Monday November 09, 2020 @08:20AM (#25034471)
the markets? that would be bad news because the markets have had no touch with reality for a long time
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by TomGullen on Monday November 09, 2020 @08:53AM (#25034796)
That's the popular view but I don't think they've been as irrational as lots of people think.
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by cblconfederate on Monday November 09, 2020 @09:00AM (#25034863)
more random than irrational
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by bamboozled on Tuesday November 10, 2020 @06:02AM (#25044615)
The markets have been reacting positively for months, what’s new here ?
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by standardUser on Monday November 09, 2020 @10:20AM (#25035638)
I think the data is what indicates this is the beginning of the end. All of the leading Western vaccine candidates showed very strong Phase 2 results. Now, we have the first vaccine showing very strong initial Phase 3 results. This is basically the best case scenario.
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by untog on Monday November 09, 2020 @07:27AM (#25034028)
The markets seem to wildly yo-yo with every piece of negative and positive news. Case in point: Zoom is currently down 10% but I’ll bet it will have rallied by the end of the day.
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by Zenbit_UX on Monday November 09, 2020 @08:48AM (#25034734)
It's more than zoom, everything that's gone up from the pandemic is dropping: amzn, meli, jmia, se, shop, sq. The markets had them valued at a premium due to their monopolies in the pandemic but retail stocks are now trending up premarket: bbby, etc.
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by untog on Monday November 09, 2020 @09:31AM (#25035155)
My point is that all of this is gut reaction to a headline, not a nuanced analysis of vaccine efficiency, roll out plans etc etc. Things could turn right around again once those details are resolved.
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by gustavf on Monday November 09, 2020 @08:41AM (#25034680)
I'll take the other side of that bet.
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by TomGullen on Monday November 09, 2020 @08:52AM (#25034779)
I don't think it's worth looking at individual stocks in this instance, and I think you're not understanding why Zoom would drop on good vaccine news.
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by untog on Monday November 09, 2020 @09:28AM (#25035121)
I am absolutely understanding why Zoom would drop on good vaccine news. It’s not a complicated connection!

My point is that the market overreacts to every piece of good or bad news, then settles down as the full implications become clear. There are still a lot of unanswered questions about the vaccine, how we handle rollout, etc etc etc. That’s not really considered in immediate reactions like this, it’s all gut feeling.

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by ro-_-b on Monday November 09, 2020 @07:19AM (#25033963)
I remember that in March somebody posted here an entry saying that mutation of the virus will make vaccinations only useful in the short term. Were these concerns already addressed at this stage?

We have seen mutations due to minks recently which could make the vaccinations ineffective. These mutations might have been controlled but similar situations may arise in the next years.

For these reasons I am not entirely sure this is the beginning of the end.

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by Wintamute on Monday November 09, 2020 @07:47AM (#25034168)
Coronaviruses like SARS-COV-2 mutate relatively slowly and minimally compared to others. So mutation isn't expected to be a huge concern, unlike say influenza which mutates relatively rapidly and requires an annual tweak to the vaccines.

What's more, any new strains we do see spreading more widely will do so because their mutations confer a competitive advantage. In practice that usually means more drift towards higher infectiousness but less severe symptoms - the same mechanisms that have left us with 4 other endemic but mild common cold coroanviruses.

The new SARS-COV-2 vaccines may be a useful tool to get us over this hump where the virus is still novel to a large proportion of the population, but are unlikely to be required indefinitely.

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by bipson on Monday November 09, 2020 @08:50AM (#25034758)
It was said (arguably in the news, so, nobody knows if true) that the mutation found in the mink populations in Denmark has a significantly different response to antibodies, in particular, they are less effective.

This is why OP is asking and mentioning the minks in Denmark.

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by aphextron on Monday November 09, 2020 @07:42AM (#25034127)
>I remember that in March somebody posted here an entry saying that mutation of the virus will make vaccinations only useful in the short term. Were these concerns already addressed at this stage?

Regardless of whether the mutations are significant enough to affect vaccine efficacy, it won't likely be a problem. These new mRNA vaccines have a development/production time measured in weeks and months, not years. It changes vaccines from a hardware problem to a software problem. Once the underlying delivery technology is proven safe and effective, reacting to new strains will be as swift as patching a codebase. It's hard to overstate what a massive advance in vaccine tech is happening here.

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by aj_g on Monday November 09, 2020 @10:17AM (#25035618)
Fascinating--do you have any links to further reading/watching about this?
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by aphextron on Monday November 09, 2020 @10:54AM (#25036032)
>"Fascinating--do you have any links to further reading/watching about this?"

https://www.nature.com/articles/nrd.2017.243

The basic idea is that now rather than needing to culture live viruses in chicken eggs, we can literally just encode the RNA for a specific antigen into a synthetic substrate and produce vaccines through a chemical process like any other drug. The RNA is then absorbed into your cells, and your own body creates the proteins which stimulate an immune response.

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by carlmr on Monday November 09, 2020 @07:24AM (#25034008)
Considering Denmark is also one of the richest countries on earth we can neither expect other countries to a) detect such a mutation early and b) handle the issue promptly.

So I think it's somewhat likely that we'll see mutations emerge all over the world.

Whether this vaccine works depends on how early we get most people vaccinated. It may only be a short term patch, which we will see once it's rolled out, you can't really predict the long term without any measurements.

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by input_sh on Monday November 09, 2020 @07:39AM (#25034109)
Except Zoom's, which fell from 514 to 410 in less than an hour.

Really puts the nails in coffin of the whole "we're gonna work more remotely after the pandemic" narrative.

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by sethammons on Monday November 09, 2020 @07:45AM (#25034150)
Investor speculation doesn’t put nails into anything :)
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by tinyhouse on Monday November 09, 2020 @11:33AM (#25036495)
Well, stocks go up and down, nothing new. There are also too many investors who panicky buying and selling without much knowledge of the industries they buy/sell stocks.

Zoom has been doing up ~500% this year. The large fluctuations are expected. Online learning/work will continue to grow regardless of a vaccine. It's not going to be in a crazy rate like it has been this year because of covid. I'm not even talking about companies, cause that's a no brainer. I'm talking about education and hospitals. For example, the convenience of having a virtual appointment is great for both doctors and patients and it's not going away no matter what.

My opinion about Zoom. Selling because of a vaccine is pretty stupid. You should sell if you think they are over valued and not be able to compete with the big companies long term. One thing to pay attention to is their future plans. If they don't have plans to expand their product line I would worry long term. There's no problem for a company to pay for Zoom for video calls and for another company for things like slack/docs etc. But when you have companies like Google/Microsoft who package and integrate everything together, and can give you a good price for it too, then it's a concern. Google/Microsoft make many subpar products, and this year zoom showed it nicely. But they keep copying the important features and will eventually close the gap.

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by TheHypnotist on Monday November 09, 2020 @08:52AM (#25034777)
Zoom isn't going anywhere
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by randomsearch on Monday November 09, 2020 @07:45AM (#25034153)
Did it? I’m looking at ZOOM and it’s on 500
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by iso1631 on Monday November 09, 2020 @07:50AM (#25034188)
https://finance.yahoo.com/quote/ZM/

Zoom was 500 at close yesterday, in premarket trading it's dropped 13% to 435.

Nasdaq open at 1430 GMT

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by mettamage on Monday November 09, 2020 @07:47AM (#25034171)
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by strombofulous on Monday November 09, 2020 @07:45AM (#25034155)
I don't understand, aren't future events supposed to be already considered in the stock price? It's not like a vaccine was unpredictable
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by OJFord on Monday November 09, 2020 @08:30AM (#25034570)
Well, stock prices move right? If everything was always perfectly priced in, they'd be constant. This movement or reaction is exactly that pricing in of future events given a change in information.
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by harryh on Monday November 09, 2020 @08:36AM (#25034633)
A vaccine was (and still is to some degree), in fact, unpredictable.

When will one be developed?

How effective will it be?

Will it have any negative side effects?

How hard will it be to manufacture and distribute?

All of these are important questions that were hard to predict. Today's announcement sheds some light on possible answers to these questions, so this new information is being priced into the market.

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by sfblah on Monday November 09, 2020 @10:40AM (#25035852)
If anything, I'd expect this to be bearish, because it might cause the Fed to stop printing money.
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by Cthulhu_ on Monday November 09, 2020 @07:54AM (#25034231)
Yeah, but investors seem to want to hold on to stocks for as long as possible (dividends? I don't know how that works, as far as I know holding stock for dividends is nowhere near as profitable as speculating)
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by triangleman on Monday November 09, 2020 @12:32PM (#25037201)
Reuters calculated [1] that the average holding period for stocks is down to 5.5 months recently. See the chart on that page, it has been as high as 8 years in the past.

Because of day traders and HFT, it's hard to say how long your average investor holds a stock, but it's fair to say that some hold it for a long time and others "speculate" most of the time. The speculators probably have a greater impact on the movement of a stock, but over time it must move in line with the performance of the company.

The price of a stock is thought to be a "risk adjusted present value" of the underlying company. Even if you could be 100% sure a company would make X dollars per year in perpetuity, the price would not be infinite. Instead each year of earnings is "discounted" by risk, inflation rate, the cost of borrowing money, the value of competing investments, and other factors.

If it was assumed by investors that Zoom would make lots of money for the next 5 years, and then make very little money, and this news meant they would only make lots of money for the next 3 years, then that will have an impact of 2 years worth of discounted earnings immediately.

(of course it's not like Zoom pays or is planning to pay a dividends but there's still an underlying value, for instance they could be purchased by a larger company that does pay dividends.)

[1] https://www.reuters.com/article/us-health-coronavirus-short-...

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by patwolf on Monday November 09, 2020 @08:26AM (#25034527)
It doesn't always work like that. It's clear to some folks that ZM will decline based on the fact that a COVID vaccine was virtually inevitable. However, there are lots of investors, mostly retail investors, that are willing to buy a stock without fully pricing that in. E.g. Tim's dad sees that Tim is using Zoom for school and decides it would be a good investment. Other investors are willing to buy ZM for short-term gain as long as they can get out before it crashes back to reality.

The same thing happened to Hertz, which even after declaring bankruptcy and almost certainly being worthless continued to trade at a healthy volume. In fact, Hertz tried to get approval to dilute and sell more shares to capitalize off the fact that people were buying their worthless stock.

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by rubidium on Monday November 09, 2020 @08:15AM (#25034435)
Kind of, but two things: (1) the markets are irrational. And (2) real events (eg 100% certainty that we have a vaccine passing phase 3 right now) are different than 90% chance that we’ll have a vaccine in the next y months.
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by mettamage on Monday November 09, 2020 @07:55AM (#25034240)
+1

Thanks for putting it so succinctly. I really hope someone who knows a thing or two about the efficient market hypothesis can elighten us a bit.

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by TomGullen on Monday November 09, 2020 @08:57AM (#25034828)
If a stocks price is $100, and tomorrow there will be a news event where there is a 50% chance it will be worth $50, and a 50% chance it will be worth $200, the trading value today should probably be around $125 (it's expected value or EV, $200 + $50 / 2).

When the defining event actually occurs, it will either move from $125 to $50, or $125 to $200.

So the news event in this example is priced in at $125, but there is still scope for big moves when certainty is realised.

Obviously in real life the values are never as certain. In the above example if the stocks ever trades < $125 before the event, you would make money in the long run.

EMH shouldn't be taken seriously as the market actors are compromised of irrational humans.

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by _fourzerofour on Monday November 09, 2020 @08:02AM (#25034311)
Just going to plug a book here that was an awesome read in my undergrad on that topic, and the history of quant finance over the 20th / early 21st centuries: https://byjustinfox.com/myth-of-the-rational-market/
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by mettamage on Monday November 09, 2020 @08:29AM (#25034557)
Thanks ... (it seems I can't find your username, how odd)

I really appreciate the guidance as I'm quite new to it. Especially so because you're enthusiastic about this book :D

Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by baq on Monday November 09, 2020 @10:34AM (#25035790)
everybody who knows about efficient market hypothesis knows that it's assumptions aren't applicable to the real world and it doesn't really matter; the real problem is those folks who mindlessly repeat propaganda about markets being rational or fair or generally doing the right thing when they clearly aren't.
Re:Covid vaccine: First ‘milestone’ vaccine offers 90% prote... by andrepd on Monday November 09, 2020 @08:09AM (#25034385)
Well, it's bullshit x)