Re:Ask HN: What are some available force multipliers that mo...
by btrettel on Sunday August 09, 2020 @09:40AM
(#24099569)
I'd recommend against regularly taking anticholinergic drugs like diphenhydramine because they've been fairly clearly linked to cognitive decline in the elderly when taken regularly: https://en.wikipedia.org/wiki/Diphenhydramine#Adverse_effect...
It's worth noting that many allergy meds (like diphenhydramine) are anticholinergic, but only ones which pass the blood-brain barrier are linked to cognitive decline. So newer allergy meds like cetirizine and loratadine are better.
Re:Ask HN: What are some available force multipliers that mo...
by esperent on Sunday August 09, 2020 @10:18PM
(#24104838)
Your link says anticholinergic use later in life has been linked to cognitive decline, not that use by young people results in cognitive decline later in life.
Re:Ask HN: What are some available force multipliers that mo...
by btrettel on Monday August 10, 2020 @07:29AM
(#24108079)
I linked to Wikipedia, but I originally read the abstract of a different study, which might have examined diphenhydramine specifically rather than many anticholinergic drugs. The abstract of the article cited on Wikipedia makes it clear that it's a cumulative effect, and that they studied outcomes in older adults. So I think Wikipedia describes the research incorrectly.
Re:Ask HN: What are some available force multipliers that mo...
by newsbinator on Sunday August 09, 2020 @09:28AM
(#24099494)
For those people who feel groggy or nauseous/headachy in the morning after Melatonin, try taking 0.3mg. You might find it has the same effect with less pronounced side effects.
(I am not a doctor)
I also started taking 1mg melatonin an hour before I want to sleep. That works wonders for me.
https://slatestarcodex.com/2018/07/10/melatonin-much-more-th...
... and, umm, mindfulness, I guess.