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Re:Antibody Tests Point to Lower Death Rate for the Coronavi... by javagram on Thursday May 28, 2020 @04:59PM (#23342540)
This headline doesn’t seem to match the body of the article:

> "The current best estimates for the infection fatality risk are between 0.5% and 1%," says Caitlin Rivers, an epidemiologist at the Johns Hopkins Center for Health Security.

> That's in contrast with death rates of 5% or more based on calculations that included only people who got sick enough to be diagnosed with tests that detect the presence of virus in a person's body.

> And the revised estimates support an early prediction by Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases and a leading member of the White House coronavirus task force. In an editorial published in late March in The New England Journal of Medicine, Fauci and colleagues wrote that the case fatality rate for COVID-19 "may be considerably less than 1%."

Unless “First Thought” simply refers to people who are unfamiliar with how figures such as CFR are calculated. I’ve been seeing the 1% number repeated by scientific figures for months.

Here is a Medium article from a month ago saying the same https://medium.com/@gidmk/what-is-the-infection-fatality-rat...

> From the 13 studies — including 4 models, 4 observational studies, and 5 pre-prints of one kind or another — there was an overall estimate of 0.75% infection-fatality rate, with the 95% confidence interval ranging from 0.49% to 1.01%.

Re:Antibody Tests Point to Lower Death Rate for the Coronavi... by nodamage on Thursday May 28, 2020 @05:32PM (#23342950)
Here is a WHO report from February saying the same thing:

> Modeling is a helpful tool to try to account for missed cases, such as those that are mild cases potentially missed in current surveillance activities, and the time lag between onset and death. Using an estimated number of total infections, the Infection Fatality Ratio can be calculated. This represents the fraction of all infections (both diagnosed and undiagnosed) that result in death. Based on these available analyses, current IFR estimates range from 0.3% to 1%. Without population-based serologic studies, it is not yet possible to know what proportion of the population has been infected with COVID-19.

https://www.who.int/docs/default-source/coronaviruse/situati...

Re:Antibody Tests Point to Lower Death Rate for the Coronavi... by acqq on Thursday May 28, 2020 @06:34PM (#23343736)
It is a report dated 19th February! Also note that this estimate is based exclusively on the Chinese data(!) and that it practically confirms that the Chinese data were usable for the estimates even as there were doubts spread by the media and politicians. Specifically in the same report it is written (1):

"Using an estimated number of total infections, the Infection Fatality Ratio can be calculated. This represents the fraction of all infections (both diagnosed and undiagnosed) that result in death. Based on these available analyses, current IFR estimates range from 0.3% to 1%."

And then:

"Without population-based serologic studies, it is not yet possible to know what proportion of the population has been infected with COVID-19."

So even without the population-based antibody (that is what "serologic" means) data, and only using the Chinese data "as of 11 February" available to the WHO the estimate was quite good. The range depends of course also on the age structure of the population -- the countries with much more young people would have closer to the lower number, the others closer to the higher.

1) Edit: the parent post quoted the same segment later too

Re:Antibody Tests Point to Lower Death Rate for the Coronavi... by skeletor_999 on Thursday May 28, 2020 @11:46PM (#23346080)
Another consideration is whether or not the Chinese data has been reliable at later dates. The Chinese government did eject foreign journalists in March

https://www.bbc.com/news/world-asia-51938035

There have been some doubts regarding the accuracy of later numbers:

https://fortune.com/2020/04/24/china-coronavirus-data-real-l...

Re:Antibody Tests Point to Lower Death Rate for the Coronavi... by vannevar on Thursday May 28, 2020 @05:52PM (#23343209)
The article also fails to mention concerns about the accuracy of antibody tests, which is odd, given how much press I've seen on those problems in the past few days. The author covers the science beat for NPR, so it seems unlikely he wasn't aware of the recent antibody accuracy studies. NPR covered the story weeks ago (https://www.npr.org/sections/health-shots/2020/04/15/8344974...).
Re:Antibody Tests Point to Lower Death Rate for the Coronavi... by s1artibartfast on Friday May 29, 2020 @12:21AM (#23346223)
Here is the link a meta analysis of IFR studies to date. possibly the one you referenced. Nearly every study to date has been in this range. Other reports have been based irresponsible pseudo journalism and alarmism.

https://www.medrxiv.org/content/medrxiv/early/2020/05/18/202...

Re:Antibody Tests Point to Lower Death Rate for the Coronavi... by DanBC on Friday May 29, 2020 @08:31AM (#23349179)
> Other reports have been based irresponsible pseudo journalism and alarmism.

Other reports were using CFR, which isn't alarmism.

Re:Antibody Tests Point to Lower Death Rate for the Coronavi... by thinkingemote on Saturday May 30, 2020 @04:18AM (#23359450)
Except the new articles that uses it caused alarm by exaggeration because the news wants our attention. The intention is not to cause alarm, but the effect was.

Politically it's also easier to make changes when one highlights the dangers. Not alarmist but certainly manipulative. Fear works and by being alarmed we have saved lives.

Re:Antibody Tests Point to Lower Death Rate for the Coronavi... by s1artibartfast on Friday May 29, 2020 @09:49AM (#23349931)
I think that many publications did not specify cfr or explain what it is. I often see death rate used interchangeably with the two