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A comment on Italy is extending its coronavirus quarantine measures to the entire country. Parent comment

Re:Italy is extending its coronavirus quarantine measures to... by Someone1234 on Monday March 09, 2020 @06:18PM (#22530487)
I'm incredibly ignorant, can someone explain why a drug used to treat arthritis might work against a Coronavirus? I just don't understand the connection/interaction, or why this was even tried originally?

Genuinely looking to learn.

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Re:Italy is extending its coronavirus quarantine measures to... by autojoechen on Monday March 09, 2020 @06:25PM (#22530567)
One of the ways the virus kills the patient is causing a cytokine storm [0][1]. And tocilizumab suppresses one of the cytokines in humans [2].

0: https://www.nationalgeographic.com/science/2020/02/here-is-w... 1: https://en.wikipedia.org/wiki/Cytokine_release_syndrome 2: https://en.wikipedia.org/wiki/Tocilizumab

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Re:Italy is extending its coronavirus quarantine measures to... by listsfrin on Tuesday March 10, 2020 @12:56AM (#22532844)
"It might be a cytokine storm".
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Re:Italy is extending its coronavirus quarantine measures to... by inferiorhuman on Monday March 09, 2020 @06:41PM (#22530697)
can someone explain why a drug used to treat arthritis

Rheumatoid arthritis is an autoimmune disease and not a "oh I'm old and I've worn down all of my cartilage" disease.

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Re:Italy is extending its coronavirus quarantine measures to... by BjoernKW on Monday March 09, 2020 @06:27PM (#22530586)
Rheumatoid arthritis is an autoimmune disorder. The severe cases who contracted the Coronavirus seem to experience an autoimmune reaction towards otherwise healthy lung tissue.
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Re:Italy is extending its coronavirus quarantine measures to... by DrNuke on Monday March 09, 2020 @06:23PM (#22530548)
The two doctors in the video say that it interferes with a similar auto-immune reaction that happens at pulmonary level because of the Coronavirus, so that it works.
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Re:Italy is extending its coronavirus quarantine measures to... by J_cst on Monday March 09, 2020 @06:22PM (#22530543)
The linked video has interesting explanation. Perhaps someone more versed may upload to YT to get a robotraslation to everybody's benefit?
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Re:Italy is extending its coronavirus quarantine measures to... by tbarbugli on Monday March 09, 2020 @06:20PM (#22530516)
it reduces the immune system reaction inflammatory reaction which can be fatal
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