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A comment on Italy is extending its coronavirus quarantine measures to the entire country.

Re:Italy is extending its coronavirus quarantine measures to... by DrNuke on Monday March 09, 2020 @06:13PM (#22530450)
Tocilizumab drug in Naples hospital seems promising: «The health of the patient suffering from covid 19, who arrived in critical condition, intubated and treated with the new drug therapy is recovering. Maybe we extubate him because his conditions have improved a lot ». They also say they got confirmation from Chinese colleagues who tested that earlier on 21 cases. The drug is now undergoing trial at Roche.

https://www.corriere.it/video-articoli/2020/03/09/dopo-cina-...

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Re:Italy is extending its coronavirus quarantine measures to... by Someone1234 on Monday March 09, 2020 @06:18PM (#22530487)
I'm incredibly ignorant, can someone explain why a drug used to treat arthritis might work against a Coronavirus? I just don't understand the connection/interaction, or why this was even tried originally?

Genuinely looking to learn.

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Re:Italy is extending its coronavirus quarantine measures to... by autojoechen on Monday March 09, 2020 @06:25PM (#22530567)
One of the ways the virus kills the patient is causing a cytokine storm [0][1]. And tocilizumab suppresses one of the cytokines in humans [2].

0: https://www.nationalgeographic.com/science/2020/02/here-is-w... 1: https://en.wikipedia.org/wiki/Cytokine_release_syndrome 2: https://en.wikipedia.org/wiki/Tocilizumab

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Re:Italy is extending its coronavirus quarantine measures to... by listsfrin on Tuesday March 10, 2020 @12:56AM (#22532844)
"It might be a cytokine storm".
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Re:Italy is extending its coronavirus quarantine measures to... by inferiorhuman on Monday March 09, 2020 @06:41PM (#22530697)
can someone explain why a drug used to treat arthritis

Rheumatoid arthritis is an autoimmune disease and not a "oh I'm old and I've worn down all of my cartilage" disease.

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Re:Italy is extending its coronavirus quarantine measures to... by BjoernKW on Monday March 09, 2020 @06:27PM (#22530586)
Rheumatoid arthritis is an autoimmune disorder. The severe cases who contracted the Coronavirus seem to experience an autoimmune reaction towards otherwise healthy lung tissue.
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Re:Italy is extending its coronavirus quarantine measures to... by DrNuke on Monday March 09, 2020 @06:23PM (#22530548)
The two doctors in the video say that it interferes with a similar auto-immune reaction that happens at pulmonary level because of the Coronavirus, so that it works.
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Re:Italy is extending its coronavirus quarantine measures to... by J_cst on Monday March 09, 2020 @06:22PM (#22530543)
The linked video has interesting explanation. Perhaps someone more versed may upload to YT to get a robotraslation to everybody's benefit?
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Re:Italy is extending its coronavirus quarantine measures to... by tbarbugli on Monday March 09, 2020 @06:20PM (#22530516)
it reduces the immune system reaction inflammatory reaction which can be fatal
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Re:Italy is extending its coronavirus quarantine measures to... by tim333 on Monday March 09, 2020 @06:22PM (#22530542)
That and some other stuff http://en.people.cn/n3/2020/0307/c90000-9665722.html

Chloroquine remains quite promising for the early stages http://news.southcn.com/nfplus/gdjktt/content/2020-03/09/con...

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Re:Italy is extending its coronavirus quarantine measures to... by agumonkey on Monday March 09, 2020 @08:45PM (#22531590)
so we're gonna a see a n-therapy to cover the whole span ?
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Re:Italy is extending its coronavirus quarantine measures to... by fspeech on Monday March 09, 2020 @06:28PM (#22530598)
Note this is a last resort move for patients in critical condition.
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Re:Italy is extending its coronavirus quarantine measures to... by DrNuke on Monday March 09, 2020 @06:33PM (#22530633)
It would serve well to avoid the collapse of hospitals’ critical units indeed.
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Re:Italy is extending its coronavirus quarantine measures to... by hokkos on Monday March 09, 2020 @07:03PM (#22530880)
cytokines storm in only one of the many ways coronavirus can kill, lungs failure, trachea obstruction from mucus, are others.
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Re:Italy is extending its coronavirus quarantine measures to... by busyant on Monday March 09, 2020 @06:19PM (#22530506)
If that turns out to be true, it's remarkable how many pathologies are related to our immune systems going haywire.
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