One of the shops I worked in used Redis as the primary datastore. While there was a lot of extra complexity around relational data (especially referential integrity), the snapshotting systems worked very well and we didn't have to worry about data loss. I don't necessarily think this was an ideal setup (I can't tell you how many headaches Postgres would have solved for us), but I think there are plenty of cases where you could use it without fear that your data will evaporate.