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Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by belltaco on Friday November 30, 2018 @12:14PM (#18570559)
Losing a lot of weight with very low calorie diets is hard, but not regaining it over the next couple of years is next to impossible.

Your body will try all the tricks in the book, it will reduce your metabolism to way below that of the person of the same weight, it will amp up your hunger hormones so much that you will think and dream about food 24/7.

Only 5 to 7% of people that lose a large amount weight are able to keep it off successfully in the medium and long term. Hope there is more research into this mechanism.

Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by SketchySeaBeast on Friday November 30, 2018 @12:18PM (#18570589)
And that's why weight loss techniques need to be treated like a new lifestyle, instead of a goal you hit and then finish. I lost 60 lbs a couple of years ago and found that 20 of those had recently crept back on, so I went on another shorter diet to get myself back on track. It's totally doable. You have to be aware and keep correcting.
Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by chosenbreed on Friday November 30, 2018 @12:25PM (#18570645)
> And that's why weight loss techniques need to be treated like a new lifestyle, instead of a goal you hit and then finish. I lost 60 lbs a couple of years ago ...

Firstly, fantastic achievement. I'm curious as to what motivated you enough to put in the effort (I'm assuming it required effort).

Secondly, I wonder if the speed/drastic nature of the weight-loss can be counter-productive. When you think about people don't become over-weight overnight. Perhaps a more gradual pace with some time for settling at various stages of the process...I'm thinking losing weight over a couple of years as opposed to over a couple of months.

Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by overgard on Friday November 30, 2018 @02:44PM (#18571999)
Not a doctor, and this is just anecdotal, but I lost 60 pounds in 3 months, a couple years ago (6'4" -- went from 260lbs to 200). So that was about 0.6lbs a day. (I think that's actually on the low range of metabolism -- some people can do more like 1-2lbs a day fasting).

Honestly, there were no side effects other than my back problems went away, I stopped snoring, and I felt better. Even with fasting, I just think your body has enough time to catch up when it's just a pound a day or whatnot. (Btw, you know what the world record for fasting is? 382 days. I'm not recommending that, I like food, but, as long as you get enough nutrients not to get something like scurvy and you consult with a doctor the human body is a lot more adaptable than people realize)

Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by SketchySeaBeast on Friday November 30, 2018 @12:30PM (#18570692)
It was my health. My snoring was bothering my wife, and I was exhibiting sleep apnea so I knew I either had to lose weight or go to a doctor, and I hate visiting the doctor.

And the time is certainly a factor - people have to set up weight loss scenarios that are sustainable over the long term. My weight loss goal was 1-2 lbs a week, so that was aggressive, but I am large enough that I can lose weight on enough calories to not feel deprived. By counting calories and making sure I had enough to enjoy myself it was a relatively easy process, once I got used to the counting and accountability.

Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by therealx on Friday November 30, 2018 @12:49PM (#18570849)
For some people, I think they shouldn't be given the false hope that "enough to lose weight" and "enough to enjoy myself" go together. Part of losing weight is a fundamental rewiring of what is "enjoying myself".
Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by SketchySeaBeast on Friday November 30, 2018 @12:53PM (#18570895)
Oh yeah. As a sweet freak, for me "enjoying myself" is a cup of frozen yogurt at the end of a day full of chicken breasts, not a plate of nachos or a whole pizza.
Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by striking on Friday November 30, 2018 @12:28PM (#18570673)
Garry's blog post about this was particularly insightful.[0] He shares a graph of his progress and how it goes both forwards and backwards, as well as the things he's learned along the way.

0: https://garry.tv/2018/10/17/fatty/

Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by SketchySeaBeast on Friday November 30, 2018 @12:34PM (#18570718)
> When you’re weighing yourself every day you need to understand that you’re creating a weekly/monthly average. What you ate yesterday isn’t going to show up on the scales the next day. If you ran around the park yesterday, don’t expect to have lost weight today.

I only weighed myself once a week for this reason. Every day can be demoralizing if you have a bloat day, but once a week gives enough to have a pretty regular drop. Whatever behaviour you do can't be considered on a day by day basis, it needs to be considered as a week of good behaviour, and then weeks and then months. You gotta stay consistent every day over the long term to expect results.

Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by tacon on Friday November 30, 2018 @02:04PM (#18571649)
I think daily weighing is important because it is hundreds of daily decisions to not eat that need to be made. Our current society makes food available at all times, and daily weighing is one part in actually thinking about our body and being mindful for at least twenty or thirty seconds each day. With the ridiculous calorie density of modern processed foods, a few minutes of mindless eating can add an enormous calorie load, without even beginning to feel full.

We hackers can geek out on the math in the Hacker's Diet[0], which goes into various smoothing algorithms and plotting styles to show the daily weight and smoothed trends.

[0] https://www.fourmilab.ch/hackdiet/

Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by SketchySeaBeast on Friday November 30, 2018 @02:44PM (#18571996)
That's fair, if that needs to happen. I found my caloric considerations where my tracking - I built a spreadsheet where I input values so I could track my daily allotment as I ate. I always tracked it before I ate it.

I worry that daily tracking could be discouraging or introduce maldaptive behaviour - you went up a lbs since yesterday, but that's because your morning poop wasn't as productive as it usually is, and now you feel like you need to go more extreme to make up for it the rest of the day.

Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by quotemstr on Friday November 30, 2018 @01:06PM (#18571036)
Nostrums like "treat it like a new lifestyle" are easy to say, but do they actually address the current public health crisis? Proposing actions that, for whatever reason, people don't actually take isn't a useful way to spend time.

What's good is what works. And honestly, drugs work today. The likes of the FDA considers them too risky, but I think they're deciding wrong.

Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by SketchySeaBeast on Friday November 30, 2018 @01:29PM (#18571290)
>Nostrums

def: A medicine

>drugs work today

....

Seriously though, the problem is that, regardless of cause, we're fat and lazy. Throwing more drugs to take care of diabetes and heart disease is robbing Peter to pay Paul.

I'm watching my boomer parents realize that medicine isn't going to help everything, and they are going to have to be accountable for their help. They've gotten much more physically active and lost weight because they are seeing that my grandfather's heart medication may be stopping the heart attacks but it isn't stopping his diabetes or inability to climb the stairs, and the gamut of surgeries are just making him more and more crippled. A pill won't solve our problems. It may solve the current health crises, but it won't stop the next one. Losing weight, eating better, and being active will solve the whole set of problems.

Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by quotemstr on Friday November 30, 2018 @01:41PM (#18571395)
One problem afflicting us now is that people eat too much, consequently weigh too much, damage their health, and balloon healthcare expenses society-wide. If a pill can make people eat less, why reject it? If a medication solves a problem, it solves a problem. You can't say "X doesn't work" when X does, in fact, work, and then expect people to take you seriously.

You're adopting a moralizing stance here, one that says that gain without pain is illegitimate. This approach has broad appeal, but it just doesn't work. For decades people have been making the same argument you're making, and it hasn't worked. It's time we try something else.

Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by SketchySeaBeast on Friday November 30, 2018 @01:47PM (#18571453)
> You can't say "X doesn't work" when X does, in fact, work, and then expect people to take you seriously. > You're adopting a moralizing stance here, one that says that gain without pain is illegitimate.

No, I'm saying that a pill won't solve the root problem. You make people skinny with a pill, you just end up with unhealthy, malnourished skinny people who insulin is all out of wack and who will still get heart attacks.

> For decades people have been making the same argument you're making, and it hasn't worked. It's time we try something else.

Are you suggesting that "throw a pill at it" hasn't been a solution for decades? We've had this belief that medical science can cure us of all our ills, and I think we are no realizing we can't. I've seen family members become shells of themselves after surgery after surgery causes them to lose as much as they got back. Pills always have trade offs, surgery always leaves scars. Maybe one day that'll be the case where a pill will solve all our problems, but it's not today.

Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by quotemstr on Friday November 30, 2018 @03:03PM (#18572129)
Nevertheless, telling people they should eat better and exercise more does not convince them to do these things. The approach you're advocating does not work. What is your alternative? More of the same?
Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by SketchySeaBeast on Friday November 30, 2018 @03:30PM (#18572342)
And throwing pills at it doesn't seem to help either - we've had weight loss pills for decades, unless THIS round is going to work.
Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by quotemstr on Friday November 30, 2018 @03:55PM (#18572539)
Many of the most effective medications were banned due to medical risks --- for example, DNP. Efficacy isn't in doubt here; safety is. IMHO, given that all other public health interventions have failed, we should relax the safety constraints on these existing medications and mitigate the risks however we can. Demanding perfection in drug development has left us with nothing, and something is better than nothing.
Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by SketchySeaBeast on Friday November 30, 2018 @04:17PM (#18572697)
"Acute oral exposure to DNP has resulted in increased basal metabolic rate, nausea, vomiting, sweating, dizziness, headache, and loss of weight. Chronic oral exposure to DNP can lead to the formation of cataracts and skin lesions and has caused effects on the bone marrow, central nervous system, and cardiovascular system.

...

Case reports have shown that an acute administration of 20–50 mg per kilogram of body weight in humans can be lethal. The lowest published fatal ingested dose is 4.3 mg/kg. Concerns about dangerous side-effects and rapidly developing cataracts resulted in DNP being discontinued in the United States by the end of 1938. DNP, however, continues to be used by some bodybuilders and athletes to rapidly lose body fat. Fatal overdoses include cases of accidental exposure, suicide, and excessive intentional exposure (overdose). The substance's use as a dieting aid has also led to a number of accidental fatalities."[1]

I would argue that's an entirely unsafe medication. That's not a drug that's short of perfection, it seems to be the sort of medication that will solve the obesity crises by actively killing people instead.

[1] https://en.wikipedia.org/wiki/2,4-Dinitrophenol

Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by drenvuk on Friday November 30, 2018 @12:21PM (#18570623)
Citations for the 5 to 7% would be nice. Here's a meta analysis that states otherwise.

https://academic.oup.com/ajcn/article/74/5/579/4737391

Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by dsp1234 on Friday November 30, 2018 @01:06PM (#18571034)
Per that study, "This analysis of 5-y weight-loss maintenance indicates, on average, that obese individuals maintained weight losses of 3.0 kg, representing a reduced weight of 3.2% below initial body weight. These individuals were successfully maintaining a weightloss averaging 23.4% of their initial weight loss at 5y"

Put another way, after 5 years, the average weight loss was ~3kg, with an average weight gain of 78.6% of the original lost weight.

Also, in general, an obese person who is obese before, and after 5 years has a weight that is ~3kg is likely still obese.

So this study basically just says that an average person isn't successful at keeping a large amount of weight, and gains most of it back. The specific statistics stated by the commenter above may not be correct, but the sentiment is definitely true.

That said, the study does confirm that very low energy diets (~800 meal replacement) beat out hypoenergetic balanced diet (~1200-1500 normal food) in long term weight maintence. Which is what the article is suggesting being implemented. So it's still not a great long term solution, but it's the better of the two non-exercise based solutions which this study evaluated.

Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by Jill_the_Pill on Friday November 30, 2018 @03:03PM (#18572132)
One consideration is that obesity has a snowball effect. I think I remember reading once that the average annual weight gain at midlife is 3 pounds. So over a 5-year period, those who made the attempt may have actually been down 15 pounds, plus the 3kg, from where they might have been if they'd continued on their trajectory.
Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by belltaco on Friday November 30, 2018 @01:39PM (#18571376)
I am on mobile and I don't have a root source for the below paragraph, maybe someone can dig it up.

> The statistics for dieters who lose weight rapidly, according to Wellsphere, a website sponsored by Stanford University, is worse. Only 5 percent of people who lose weight on a crash diet will keep the weight off. Crash diets include any unhealthy diet, from severe calorie-restriction diets to diets that consist of only a few kinds of foods.

Another study showing 5% looks like it was an old study from 1959.

Anyway, there are more modern studies proving the point. And that people gain even more weight back than they started with.

http://newsroom.ucla.edu/releases/Dieting-Does-Not-Work-UCLA...

>Several studies indicate that dieting is actually a consistent predictor of future weight gain,” said Janet Tomiyama, a UCLA graduate student of psychology and co-author of the study. One study found that both men and women who participated in formal weight-loss programs gained significantly more weight over a two-year period than those who had not participated in a weight-loss program, she said.

>Another study, which examined a variety of lifestyle factors and their relationship to changes in weight in more than 19,000 healthy older men over a four-year period, found that “one of the best predictors of weight gain over the four years was having lost weight on a diet at some point during the years before the study started,” Tomiyama said. In several studies, people in control groups who did not diet were not that much worse off — and in many cases were better off — than those who did diet, she said.

Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by klmr on Friday November 30, 2018 @12:26PM (#18570662)
This new diet is specifically tailored to avoid this yoyo effect. It’s currently not yet clear whether this is indeed the case (hence this expanded epidemiological study) but preliminary results indicate that this is indeed the case.

In other words, this specific diet (severely limited calories as well as restriction of food to almost completely liquids) reportedly helps sustaining the weight loss long-term (and is allegedly effective for around 50% of patients).

Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by jobigoud on Friday November 30, 2018 @01:11PM (#18571086)
Are you saying they stay on 800kcal/day for long-term? I'm skeptical. Usually the problem is when you switch to the maintenance diet.
Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by klmr on Sunday December 02, 2018 @09:08AM (#18582349)
No. The 800 kcal/day liquid diet is kept up for three months. However, the resulting weight loss is sustained long term.
Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by pknopf on Friday November 30, 2018 @12:19PM (#18570613)
I lost 40 pounds in 3 months, then another 20 in 3 months.

I've kept the weight off for another year.

I still eat healthy and in moderation (and occasionally fast).

I avoid sugars and high-carb foods and my body has been hovering at the same weight.

Maybe, for some people, it's harder to keep the weight off (assuming diet is the same)? Or, maybe some people don't have the mental will-power to stay on the diet that lost them the weight?

Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by chosenbreed on Friday November 30, 2018 @12:27PM (#18570666)
Superb. Clearly in your case you summoned the necessary will to lose all that weight. But I think another important factor is that you established a new lifestyle/better eating habits.
Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by vonmoltke on Friday November 30, 2018 @12:36PM (#18570735)
> But I think another important factor is that you established a new lifestyle/better eating habits.

How is it not a given that you need to do this? Your lifestyle and eating habits got you to that overweight state in the first place. Of course you will return to that state eventually if you don't permanently change them.

Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by diminoten on Friday November 30, 2018 @12:47PM (#18570826)
"Summoned" implies it's only possible for people who know the arcane secrets, I'm not personally a fan of removing people's agency when talking about something like this.
Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by alrehn on Friday November 30, 2018 @01:23PM (#18571216)
Removing agency is exactly what you should do when you're talking about a widespread problem. If I have a personal friend I'm absolutely going to tell them they can make the right choices and overcome their problems, but you can't do that with a society. You have to look at incentives and environment and change those to change widespread behavior.
Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by sidlls on Friday November 30, 2018 @01:14PM (#18571109)
In some cases at least consider this is like discussing the agency of a person addicted to narcotics.
Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by diminoten on Saturday December 01, 2018 @03:31PM (#18578752)
Generally, no.
Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by lol768 on Friday November 30, 2018 @12:17PM (#18570584)
>Only 5 to 7% of people that lose a large amount weight are able to keep it off successfully in the medium and long term. Hope there is more research into this mechanism.

Are there any studies in this area I can read that discuss the figures you've mentioned?

Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by cstansbury on Friday November 30, 2018 @01:00PM (#18570956)
>>Only 5 to 7% of people that lose a large amount weight are able to keep it off successfully in the medium and long term. Hope there is more research into this mechanism.

> Are there any studies in this area I can read that discuss the figures you've mentioned?

One example may be found in Dr. Jason Fung's book, "The Complete Guide to Fasting." Chapter 5 describes a case regarding the American TV show, "Biggest Loser", where overweight contestants lost loads of weight during the show with a low calorie diets and exercise. All except one contestant gain the weight back.

Below is the reference to the study cited in Fung's book. https://onlinelibrary.wiley.com/doi/full/10.1002/oby.21538

Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by belltaco on Friday November 30, 2018 @01:41PM (#18571396)
I referenced some things in this comment https://news.ycombinator.com/item?id=18571376
Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by philip1209 on Friday November 30, 2018 @12:16PM (#18570579)
Type II diabetes is a diet-related illness. If you cure the illness with diet, then switch back to what you were eating before - of course, diabetes will come back. These dietary changes need to be seen as new habits, not temporary changes.
Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by pknopf on Friday November 30, 2018 @12:24PM (#18570642)
Exactly this. My A1C went from 8, to 4.9. My blood sugar rarely goes out of wack, even when abused.

I eat low carb, and fast intermittently. It's my life-style now.

After eating a while for an extended period of time, my blood sugar is much more stable, regardless what I eat.

Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by Brigadirk on Friday November 30, 2018 @12:46PM (#18570822)
I thought I was getting too fat in 2015. I went on an "eat half" diet. Literally lost weight eating pizza and drinking beer, just less than I needed. Lost 12 kilos.

After this, I just ate as I felt like, with intermittent periods of damage control, where I'd revert to the diet for a few days here and there to either budget an upcoming event (e.g. Christmas), or pay for a recent one.

Works for me. Only note is to watch out with sugar & alcohol, as both can turn on the 'fuck it I WANT THIS NOW' mode, at least for me.

Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by distant_hat on Thursday December 06, 2018 @04:20AM (#18616502)
This. I've known a bunch of people who lost a large part of weight (without surgery) and kept it off and they basically turned into different people (more fun though). They restricted their eating, they worked out, often went for hikes etc. But their lifestyle was completely different before and after. They didn't bitch about turning down dessert or things like that. They seemed to actually just be a different person.
Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by brandonmenc on Friday November 30, 2018 @03:02PM (#18572124)
> Only 5 to 7% of people that lose a large amount weight are able to keep it off successfully in the medium and long term. Hope there is more research into this mechanism.

The mechanism = not staying on your "diet" permanently.

Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by DiffEq on Friday November 30, 2018 @12:31PM (#18570695)
That is why there needs to be some visible and lasting penalties...as in if you have a disease like diabetes that you can prevent or fix by simply eating better and not eating so much - then you are responsible for any and all medical costs associated with it. We don't allow insurance claims if you purposefully wreck your car or burn your house down; why do we allow this when it comes to your health?
Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by vidarh on Friday November 30, 2018 @12:59PM (#18570954)
If you think "simply eating better and not eating so much" is "simple", you don't understand people. All our evidence is that it is by no means simple for most people. It's a problem that's about as hard to deal with as drug addiction.

Furthermore, it is a social problem, in that we as a society allow businesses to exploit peoples weaknesses without covering the social costs of the problems they are causing, and given that how people around you act strongly influence how able people are to stick to a diet.

To then act as if this is down to some imaginary free will is irresponsible.

Re:Type 2 diabetes: NHS to offer 800-calorie diet treatment by DiffEq on Friday November 30, 2018 @02:58PM (#18572096)
Well I "simply" don't eat the stuff or over eat. O.k so maybe I am some anomaly but I don't think so. Sure some people take a little more incentive and that is why I propose to provide them with some incentive - which would be that if they knew, or saw, that their health care costs are no longer covered if they cause their health issues then a large amount of people would start changing their ways. People need to be made responsible for their decisions; this means they must pay for their actions - if they are not held accountable then they, in general, will not act in a responsible way. Making people responsible will turn the social tide.