The fact that some individuals' immune system let it through hint that there is a more important causal issue somewhere.
Herpes may be a simple symptom, not a disease.
And maybe it's a symptom of a condition that is similar to the one that let Alzheimer’s set in.
Who knows, maybe Alzheimer's is a symptom too of a more deep, complex and subtitle disorder.
Assuming there's some preventable cause or vector, anyway.
At this point there are simple too many of these and the combinations even larger.
_If__ such things contribute to anything, we'll likely never know.
Actually, there's quite a lot we can do, and relatively cheaply, too: https://www.healthline.com/health-news/why-we-still-dont-hav... :
However, Clark said a phase III trial would have cost $150 million and taken three years. In the end, the company’s board and investors were “unwilling to take on the investment.”
"We" are just choosing not to do it.
This RNA serves to keep the virus latent and quiet, perhaps for years. Only when this suppressive RNA is washed out of the nucleus does replication begin.
The idea was to remove all of this RNA everywhere in a controlled manner while administering acyclovir or another antiviral. I don't know what inaccessible resovoirs remain for the herpes family. The brain would be particularly hard to reach.
Such a treatment might also trigger shingles, mono, and ks all at once if it was too widely targeted or if the antiviral wasn't strong enough.
https://www.researchgate.net/publication/262422871_Antigenic...
Peter Thiel's investment firm threw USD$7mm at Rational Vaccines last year, but unfortunately as far as I'm aware they are mired in a legal battle since their first human "clinical trial" was performed outside the supervision of the regulators. Rational Vaccines (Prof. William Halford) developed Theravax, a live-attenuated vaccine. It operates on the same principle as the vaccine developed by AuRx, but IIRC, not quite as safely and effectively.
Aside from this, our only (as far as I'm aware) hopes are CRISPR efforts from either Editas or Excision Bio, or an antiviral developed by NanoViricides.
You'd think all the celebrities who buy $100mm mansions could do something about it (since statistically they probably all have it), but no.
If we're lucky, Thiel's investment will turn good. I'm sure his associates aren't morons and they didn't invest in a dud. Last I heard, Rational Vaccines are ramping up to proper human clinic trials within FDA regulations. We just need to wait.
Excision Bio should be running human clinical trials either next year or the following, and our collective understanding of CRISPR is expanding rapidly. So that's something to be excited about. Not that this makes waiting any less painful for sufferers.
There is no cure for HSV.
The current state of care is periodic retroactive therapy in the case of an outbreak, or continuous prophylaxis which isn't completely effective due to lack of bioavailability.
People still get outbreaks during prophylaxis, and people still shed the virus when symptoms aren't present.
I believe the drug you are talking about is Pritelivir/Amenamevir, currently marketed in Japan under the name Amenalief.
Am I correct? If so, I was not aware they are available in India for such a low price.
http://www.who.int/news-room/fact-sheets/detail/herpes-simpl...