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Re:Link Between Alzheimer’s and Herpes by jopsen on Saturday July 14, 2018 @03:51AM (#17529322)
Well, we could work on a cure and vaccine for HSV-1. Whether or not it mitigates Alzheimer's I sure would pay a lot of money to not deal with cold sores every winter.
Re:Link Between Alzheimer’s and Herpes by yakshaving_jgt on Saturday July 14, 2018 @04:32AM (#17529411)
There already is an effective therapeutic vaccine. There has been for years. The problem is, it's only done a phase II clinic trial. They need USD$20mm to move through the third phase, and onto mass production. The company is called AuRx. If anyone has twenty million in their pocket, please end herpes for all.

Peter Thiel's investment firm threw USD$7mm at Rational Vaccines last year, but unfortunately as far as I'm aware they are mired in a legal battle since their first human "clinical trial" was performed outside the supervision of the regulators. Rational Vaccines (Prof. William Halford) developed Theravax, a live-attenuated vaccine. It operates on the same principle as the vaccine developed by AuRx, but IIRC, not quite as safely and effectively.

Aside from this, our only (as far as I'm aware) hopes are CRISPR efforts from either Editas or Excision Bio, or an antiviral developed by NanoViricides.

Re:Link Between Alzheimer’s and Herpes by echelon on Saturday July 14, 2018 @12:10PM (#17530869)
Have they thought about crowd funding a raise? I'd contribute. Surely they can do something outside of institutional investing.
Re:Link Between Alzheimer’s and Herpes by yakshaving_jgt on Saturday July 14, 2018 @02:11PM (#17531514)
Yeah, there have been many attempts at crowdfunding this stuff. As it turns out, nobody cares that much.

You'd think all the celebrities who buy $100mm mansions could do something about it (since statistically they probably all have it), but no.

If we're lucky, Thiel's investment will turn good. I'm sure his associates aren't morons and they didn't invest in a dud. Last I heard, Rational Vaccines are ramping up to proper human clinic trials within FDA regulations. We just need to wait.

Excision Bio should be running human clinical trials either next year or the following, and our collective understanding of CRISPR is expanding rapidly. So that's something to be excited about. Not that this makes waiting any less painful for sufferers.

Re:Link Between Alzheimer’s and Herpes by delbel on Saturday July 14, 2018 @03:03PM (#17531799)
wait, hold on. there's an effective drug that cures HHV-1 and alot of other things include the cryptoplasma cat parasite virus, and Herpies 2. There's no toxic limit (people take 4g twice a day with no side effect, way over what is needed to kill it) and it works within 48-72 hours. We don't need a vaccine. It could be sold over the counter. There are two groups that have separate method of actions, so if it fails there's another one.
Re:Link Between Alzheimer’s and Herpes by yakshaving_jgt on Monday July 16, 2018 @04:08AM (#17539560)
This is categorically false.

There is no cure for HSV.

The current state of care is periodic retroactive therapy in the case of an outbreak, or continuous prophylaxis which isn't completely effective due to lack of bioavailability.

People still get outbreaks during prophylaxis, and people still shed the virus when symptoms aren't present.

Re:Link Between Alzheimer’s and Herpes by delbel on Tuesday July 17, 2018 @12:41AM (#17547387)
if your a doctor I'll send you the name of the drugs. They came out in 2015 and are about $80 each a pill, but you can buy them in India for $.34 each.
Re:Link Between Alzheimer’s and Herpes by yakshaving_jgt on Thursday July 19, 2018 @02:56PM (#17569297)
I am not a doctor, just a relatively informed individual.

I believe the drug you are talking about is Pritelivir/Amenamevir, currently marketed in Japan under the name Amenalief.

Am I correct? If so, I was not aware they are available in India for such a low price.