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Re:Opium, Empire, and India by ultimoo on Wednesday April 05, 2017 @02:44PM (#14044488)
Having never tried any hard drugs or the mentioned concoctions, pardon my basic question -- what effects does consuming opium have? Is it like consuming modern day heroin? Does it imitate what people feel after smoking pot? Just trying to understand why people consumed it -- the article mentions pain relieving uses as well as 'taking the edge off' uses.
Re:Opium, Empire, and India by opiate_eng on Wednesday April 05, 2017 @08:09PM (#14046860)
I was an opiate addict for 10 years, and still use a bit. Never bought off the street; always got pharma connects, except for opium which I got some a local guy with some flowers. During the whole time I've been a software engineer, and done some cool stuff. I'm also bipolar, and opiates have been my treatment. Opiates don't make you dumb like pot. I'm totally functional, indeed, more functional (as evaluated by third parties inc medical professionals) when using opiates.

Opiates are amazing. They take away a lot of depression. I got up to 50mg of oxy a day, which is quite modest and very inexpensive. It made me happy. Melted away worries. At one of my startups, we got crossed by a partner, almost had to fire everyone. The stress was paralysing - business partner attempted suicide. Me? Start the day with oxy and feel ready to take on things.

Even now, it can change that morning lethargic everything-sucks-why-don't-I-binge-Star-Trek-or-kill-myself into "hey I'm gonna write some software".

The other comments describe it alright - a warm happy dream. It's quite pleasurable even if you're by yourself; you can spend hours just "nodding" off, in and out of consciousness. It's quite sublime. The peace is so powerful, that a few times when I was being self destructive and got to the edge of OD, I noticed but simply didn't care. I'm more careful nowadays, though oral opiates are quite safe if you don't act reckless.

IV opiates step it up a bit. Users talk of a rush. It's similar to an oncoming amazing orgasm x10, then the warmness floods your body and everything's perfect and you might even gasp for breath it's that good. I think part of that is just the IV, and having a huge shift so quickly. For instance, there's a rush when IV'ing midazolam (dangerous, do not use without medical supervision), right before you pass out.

I've gone off opiates a few times. It wasn't as an enjoyable life. The only downsides are constipation (eh, saves time) and possibly lower testosterone (as someone often manic, lower libido is great - but it's easy to get TRT anyways.) I've not seen much as far as long-term damage from use.

Re:Opium, Empire, and India by danmaz74 on Thursday April 06, 2017 @10:32AM (#14050819)
> I've not seen much as far as long-term damage from use

Isn't addiction the biggest problem, requiring increasingly higher doses to achieve the same effect?

Re:Opium, Empire, and India by 55555 on Wednesday April 05, 2017 @04:33PM (#14045356)
It's an analgesic. All opiates feel pretty similar; heroin and codeine are really not too different. When you take a lot of either, it feels like being wrapped in a warm blanket.

Opium IIRC is a natural mixture of morphine and codeine among some other alkaloids, but primarily those two.

You can buy opium in the US in the form of "unwashed" poppy seeds (The seeds are from the pod and are coated in opium, which is typically washed off), which I don't particularly recommend due to safety and legal reasons, but that's up to you ofcourse.

Source: I have tried my share drugs and smoked opium in rural parts of Asia several times.

Re:Opium, Empire, and India by mattnewton on Wednesday April 05, 2017 @03:06PM (#14044664)
I have never tried opium but given many painkillers are called "Opiates" I imagine they all share the same fundamental mechanism of opium and feel like different flavors of each other. Quite unlike marijuana then.

https://en.m.wikipedia.org/wiki/Opiate

Re:Opium, Empire, and India by wavefunction on Wednesday April 05, 2017 @05:46PM (#14045936)
Many opiates produce a euphoric feeling, which in practice means a general 'warmness' in the body and pleasurable mental state. The senses are dulled, time dilation is common and the stresses and concerns of life are forgotten or at least reduced in importance.

For someone experiencing pain whether physical or emotional, the opportunity to escape that pain seems to me to be understandable if not well advised.

Opium -which I have tried once- was lovely. I don't like other opiates though, they provoke a minor allergic reaction consisting of itchiness and uncomfortable warmness I did not experience with opium. These were hydrocodone and other legally and appropriately prescribed medicines for a serious injury.

Re:Opium, Empire, and India by 6stringmerc on Wednesday April 05, 2017 @03:04PM (#14044651)
Most depictions I've come across - and having been given opiates in medical situations - allude to it being like a dream-state. A bit of euphoria. Feeling so good you don't want to move. Hence the attraction for repeating the experience.
Re:Opium, Empire, and India by kleer001 on Wednesday April 05, 2017 @03:27PM (#14044806)
Re:Opium, Empire, and India by pstuart on Wednesday April 05, 2017 @04:09PM (#14045153)
Physical pain melts away and there's a sense of "feeling really good". It's not mind altering like cannabis, more like relaxed taken to the next level.

Or so I've heard....

Re:Opium, Empire, and India by tn135 on Wednesday April 05, 2017 @06:59PM (#14046477)
Opium would be a cross between pot and morphine. Its primary usage has been painkiller. Even as a child in India I remember using opium based oil as painkiller for tooth pain.
Re:Opium, Empire, and India by mtdewcmu on Wednesday April 05, 2017 @05:19PM (#14045721)
"Narcotic" means numbing, and that's an accurate description IMO. Reports of euphoria are exaggerated. It feels good if you are feeling pain or malaise and it takes the pain or malaise away. Otherwise it doesn't feel like much.
Re:Opium, Empire, and India by chimeracoder on Wednesday April 05, 2017 @05:27PM (#14045781)
> "Narcotic" means numbing

Just to be clear, for anyone else reading this, that's true in the etymological sense. But from a biological or pharmaceutical standpoint, 'narcotic' has a pretty narrower meaning, referring to a specific class of drugs (which tend to produce numbing effects, but not everything with numbing effects is a narcotic).

To make matters more confusing, law enforcement, on the other hand, uses 'narcotic' as synonymous with 'any illegal drug', whether or not it actually is a narcotic (in the biological sense) or has a narcotic effect (in the literal sense that you are referring to).

For example, the 'narcotics unit' will deal with cocaine, which is used as a topical anesthetic for numbing[0], but cocaine is very much not a narcotic from a medical standpoint.

[0] in theory, you could use cocaine for a root canal, but you're more likely to get Novocaine instead.

Re:Opium, Empire, and India by fragsworth on Wednesday April 05, 2017 @05:35PM (#14045849)
> Reports of euphoria are exaggerated.

No, they aren't. It depends a lot on the person, the specific narcotic, and the quantity taken. Some (most in my experience) people feel intense euphoria, others don't.

Re:Opium, Empire, and India by mtdewcmu on Wednesday April 05, 2017 @05:45PM (#14045929)
The "euphoria" is situational. It's like alcohol. Drinking alone is usually not much fun.
Re:Opium, Empire, and India by Nursie on Wednesday April 05, 2017 @05:20PM (#14045732)
Having experienced euphoria once or twice from codeine (>100mg) I would dispute that.
Re:Opium, Empire, and India by elevensies on Wednesday April 05, 2017 @05:32PM (#14045816)
2nding this, I've been given IV narcotics a couple times in-hospital and it created a noticeable feeling within ten seconds or so. I would say the closet analog I can think of would be slipping into a warm bath, if slipping into a warm bath also made you feel a little drunk.

My only experience with numbing is the dental anesthetic they use in your mouth, which I don't recall producing much sensations but it does noticeably take sensation away.

Re:Opium, Empire, and India by chimeracoder on Wednesday April 05, 2017 @05:42PM (#14045902)
> My only experience with numbing is the dental anesthetic they use in your mouth, which I don't recall producing much sensations but it does noticeably take sensation away.

Those aren't narcotics (most likely). It was probably Novocaine or Lidocaine. Those drugs end in -caine because they're all part of the same family as cocaine, which is not actually a narcotic (but does have euphoric effects at sufficient dosing levels!).

Topical use of any of those drugs, however, will likely not produce euphoria.

Re:Opium, Empire, and India by mtdewcmu on Wednesday April 05, 2017 @05:47PM (#14045950)
If you were given narcotics in the hospital, then there must have been a reason. I said that if you have pain, and the drug takes it away, it feels good.
Re:Opium, Empire, and India by Nursie on Thursday April 06, 2017 @03:47PM (#14053961)
I wasn't in hospital, or in any pain. The euphoria is very real.

For the benzodiazepine class of drugs it's a little less clear cut - people who take them recreationally may well be alleviating stress or anxiety and finding that pleasurable. Opiates.... nah.

Re:Opium, Empire, and India by mtdewcmu on Thursday April 06, 2017 @04:02PM (#14054067)
Note that there are many reasons for why anecdotes don't count as evidence.

I thought that I felt euphoria the first time I took codeine (but I honestly wasn't sure). I have taken codeine since and was never able to replicate that euphoria.

IME with opioids, there will be times when they feel good (or seem to), but those good feelings are frustratingly hard to replicate. I've taken a skeptical look back at all my use and concluded that the drugs simply don't have the power to cause euphoria all by themselves. They can be sort of like a social lubricant, and they can be reliably good when I feel like complete shit. But I never figured out a way to conjure euphoria on command using just opioids.

Re:Opium, Empire, and India by Nursie on Friday April 07, 2017 @10:56AM (#14060187)
I've had codeine euphoria multiple times. I'm pretty sure the euphoric effects of opiates are quite well documented.

I'll throw it right back at you - your own personal experiences are worth about as much as mine when it comes to medical evidence, not a lot.

Re:Opium, Empire, and India by mtdewcmu on Friday April 07, 2017 @05:17PM (#14063567)
There is hard evidence here[1]. Less than 5% of people reported euphoria in clinical studies of OxyContin.

[1] http://www.rxlist.com/oxycontin-drug/side-effects-interactio...

Re:Opium, Empire, and India by elevensies on Wednesday April 05, 2017 @06:31PM (#14046269)
In once case it was prior to the pain being inflicted -- for a scheduled medical procedure.
Re:Opium, Empire, and India by mtdewcmu on Wednesday April 05, 2017 @07:27PM (#14046629)
I believe you. I don't think the buzz would happen consistently if you tried to replicate it over and over. It could have been your anxiety going away, or it could have been the placebo effect.

One could easily resolve the question of whether opioids cause euphoria by doing a double-blind clinical study. I would love to do that study, in fact.

Re:Opium, Empire, and India by mtdewcmu on Wednesday April 05, 2017 @08:21PM (#14046911)
Actually, I remembered that there are relevant results from clinical studies that are available. Here are the side effects of OxyContin.[1] (Euphoria is considered a side effect.) The most commonly-reported side effects were constipation, nausea, and somnolence. If you look down further, you can see that both euphoria and dysphoria were reported rarely.

[1] http://www.rxlist.com/oxycontin-drug/side-effects-interactio...

Re:Opium, Empire, and India by opiate_eng on Wednesday April 05, 2017 @08:14PM (#14046879)
They already do these studies to test opiates vs other painkillers. Opiates kick ass.

Or maybe you're right: they just take away pain. But it turns out a lot of us have existential pain so it works all the time.

Re:Opium, Empire, and India by mtdewcmu on Wednesday April 05, 2017 @08:29PM (#14046945)
The worse you feel, the more you will enjoy opiates.