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Re:Scientists want to create ‘red teams’ to challenge climat... by hutzlibu on Wednesday March 29, 2017 @03:55PM (#13989973)
"and as somebody who sees the DNA damage in whole genome sequencing of lung cancers from smokers, boy is he ever stupidly wrong there"

Hm, but does the dna in those lungs look much different, than the lungs of nonsmoking people with lungcancer? (Seriously asking)

Re:Scientists want to create ‘red teams’ to challenge climat... by epistasis on Wednesday March 29, 2017 @04:30PM (#13990273)
Yes, the differences are massive. There's a huge signature of "bulky adduct" repair in smokers' samples. This looks different than, say, UV damage. See, for example, signature #4 from this paper:

http://www.nature.com/nature/journal/v500/n7463/full/nature1...

Re:Scientists want to create ‘red teams’ to challenge climat... by hutzlibu on Wednesday March 29, 2017 @04:56PM (#13990505)
Thanks, thats interesting
Re:Scientists want to create ‘red teams’ to challenge climat... by nonbel on Wednesday March 29, 2017 @05:57PM (#13990986)
>"All cancers are caused by somatic mutations"

Its strange that epistasis cites that paper so freely since he has expressed skepticism about this idea in the past. In fact I may have discussed that exact paper with him awhile back. The layperson probably wouldn't realize it but this is a very hubristic first sentence, almost purposefully offensive.