This is, in principle, a problem. We unfortunately have no way to measure the speed of light in andromeda, unlike what we can here on earth, so we really have no idea if our astronomical models are wrong given the non-constancy of the speed of light in andromeda or elsewhere.
So, yes, in principle not being able to repeat science experiments everywhere in the universe is a problem. However, I think if one thinks a little less broadly, testing newtonian gravity in say, Italy and also in China shows at least across the Earth, the phenomenon is similar. Then, at least one can say, "certainly, gravity is the same in Italy and China, and perhaps across the surface of the Earth." That is a stronger statement than "gravity is this way in Italy." Ordering claims by "scientific goodness", we can say that
Gravity is the same *across the universe* > gravity is the same across the Earth
> gravity is in Italy
My point here is that even if one can't fulfill the extreme of testing theories everywhere in the universe, one can progressively prove stronger and stronger statements regarding the validity of scientific theories.Somewhere the LHC stands between "the SM is validated across the universe" and "the SM is validated at one detector at the LHC". Yes, it would be "better" if the Higgs was found at other experiments, but the current situation is "better" than if the Higgs was found at one detector there and not in any other. Repeatability, like everything in science, is not a binary step function but is some continuous function over the domain [0,1].
https://en.wikipedia.org/wiki/Gravitational_constant#History...
But it does point at one measurement of G on cosmological timescales and distances from 2006:
https://arxiv.org/abs/1402.1534
There are other papers with similar measurements published in the past two decades.
That isn't a particularly fruitful approach since it doesn't permit any real discovery - it's rather brain-in-a-jar - but it is still something you have to assume away.
Since these operate in concert across the observable universe, and themselves involve various other interactions (elements, strong and week nuclear forces, gravity, speed of light, rates of hydrogen fusion, etc.), we can conclude that either there is no appreciable change in any of the underlying fundamental constants or that change occurs in a compensated fashion such that no net change is detectable.
The second fails Occam's Razor. The conclusion that the laws of physics appear to be similar throughout observable space seems robust.
In particular, you're making super-strong statements like "be all and end all of what defines 'science'" -- that's not what I see in the article. The article is reasonably pointing out that we have a repetition crisis and that more emphasis should be placed on it. That's not the various super-strong things you're claiming you see in it.
The title is picked by editors to get the most people to click on it.
You miss all nuance.
It's becomes very quickly apparent to those who've read the article when others comment without having read beyond the title.
But that doesn't matter, because it is not the experiment you are trying to replicate, is the effect or the observation.
Carefully changing the design of the experiment can allow to verify that your explanation of the effect or observation is accurate.
Of course, if the change the experiment too much, a failure to replicated will have less useful information.
So I think what has to occur is a gradual "loosening up" of the controls from strict replication to weak replication, with both types of replication giving information about the effect you are testing: its validity and its generality, respectively.
Similarly, I am not saying that you don't need to repeat - just that it isn't the be all and end all of what defines 'science'. Supporting this interpretation is that I mentioned DAMA. Nobody is accusing them of not taking care, but nobody really believes the result either.