That might help, but it depends what problem you're trying to solve then - if everyone was using the same platform, then it would be easy for adblockers to block it.

If part of your pitch is that you avoid adblockers, then once you get big enough you'll constantly be fighting an uphill battle.

I was just thinking of ye olde self-service in-house ad vendor, server, statter. If the static ad assets were coming from the same domain, how would an adblocker notice them?

well instead of blocking googleads.com/, they would just block nytimes.com/googleads/

Obviously in execution it would be different, but I hope you get the idea.

Edit: I think self-served ad platforms are one way forward, but it depends on what problem you're trying to solve.

If I were designing this system, the paths would look something like nytimes.com/e2be6560/d570/xxx-yyy-zzz(.jpeg/.js/.html/etc).