SSDs need additional circuitry, chips and memory, but MicroSD cards aren't 100% flash either. This shows that the ceiling is very high even with current lithography.
My guess is that there's just not much market for a $200k+, 50 TB 2.5" drive, but it would be possible to make in high volume production.
If you need storage capacity, traditional hard drives will easily beat it in terms of TCO.
If you need IOPS, it's much better to use an array of smaller high performance drives.
I could picture it being useful in some military and space exploration applications but that's about all.
There's little reason to pay a massive premium for huge SSDs if your controllers limits you to a small percentage of the potential capacity of the drive. So instead you get things like the PCIe cards with 4+ controllers that gets RAID'ed together by the drivers.
As the controller bandwidth catches up, I'm sure that'll change.
Doubful, since they are not radiation hardened.
I could rather see a market for smaller size SSDs which contain lots and lots of chips and thereby have their own RAID subsystems.
one can get near the same performance for much cheaper by using consumer electronics with redundant systems and a voting mechanism between systems.
The Bleak Future of NAND Flash Memory: http://cseweb.ucsd.edu/users/swanson/papers/FAST2012BleakFla...