News for hackers. Stuff that matters.
Re:Low cholesterol targets cut cardiovascular events by 33% by yfw on Thursday October 29, 2026 @01:20AM (#50284845)
He also recommends people take rapamycin for longevity...
Re:Low cholesterol targets cut cardiovascular events by 33% by esperent on Thursday October 29, 2026 @02:19AM (#50285149)
It's a while since I read the book but what I remember is him saying that he personally chooses to use it but the evidence is not strong enough to give a definite recommendation so basically, make your own choice.
Re:Low cholesterol targets cut cardiovascular events by 33% by jvanderbot on Thursday October 29, 2026 @08:53AM (#50288160)
The book is overall excellent and extremely data driven. I have no idea why a book recommendation, on topic, can get downvoted on HN nowadays.
Re:Low cholesterol targets cut cardiovascular events by 33% by esperent on Friday October 30, 2026 @03:39AM (#50300848)
Because outside of a few narrow technical spheres the HN hivemind isn't data driven, it's cynicism driven.
Re:Low cholesterol targets cut cardiovascular events by 33% by yfw on Friday October 30, 2026 @05:23PM (#50310331)
The problem is what he presents is not scientific or medical consensus. The data is on animal studies and it is irresponsible to push a prescription medication for not its intended purpose
Re:Low cholesterol targets cut cardiovascular events by 33% by DANmode on Thursday October 29, 2026 @06:55PM (#50297396)
In the context of new models showing cell identity drift being a threat to longevity (vs simple cell breakdown over time), controlling “low-level” and chronic infection makes more and more sense.