Highly depends on the person. Over 6 feet tall with screws and rods holding my spine together, even a lie flat is not very comfortable, and not having to spend my first day or two at my destination decompressing before I actually enjoy the trip would be pretty valuable to me. The only way to achieve that is less travel time, but even so I'm not sure reducing the time in air would be enough when you add in travel to and from the airport, plus taxi time on the runway. It wouldn't be nothing, though, and I'd definitely pay for it if it made a difference.

Problem is broad market trends don't care about me personally. There have to be a lot of people like me with both sufficient injuries and sufficient money and there probably are not.