The physical bump helps you type without bottoming out with practice it helps a lot with RSI, at least from my N:1 experience.
After switching to a split keyboard my pain went away, and I think I learned that at least for me it was caused by exactly these symbols - on both US QWERTY and Colemak when you constantly type [];:{}| and so on, your pinky has to reach over to do it. At least for me that meant contorting my hand a bit to reach over. On my split keyboard all the symbols are behind a layer on the home row, and I barely use the pinky for anything, which fixes the issue. I also learned to hover while switching to the split keyboard, but that did nothing for my wrist pain when going back to my laptop's built in keyboard - after a full day of programming there the pain is back.
On a completely standard rectangular-block keyboard, I don't use pinkies to type. Actually, I do use my left pinky to hit left shift. But that's it.
Going to a doctor should also be high on the list, but unfortunately, I have yet to see one willing to do a proper diagnosis. My experience there is more than mixed, so you have to experiment yourself.
FWIW, all a doctor did for me was affirm my self-diagnosis and life-style adjustments. Surgery in this area looked quite grim on my last purview so I am not sure a doctor would serve much for most in this regard.
I tried all manner of keyboards over the years, and in my opinion, none of them solve RSI. I'm now back to a standard qwerty for the same reason as OP - they're just immediately available everywhere.
What did help my no-longer-existent RSI was simple - I don't rest my wrists any more like I was taught in high school typing class (by an instructor that would whack our hands with a ruler if we were caught resting our wrists).
I do have a bit of De Quervain's Tenosynovitis from the mouse, but I'm solving that with one of those hand stretchers that hook to your fingers and provide resistance when opening the hand. 100 reps a day (25x4) and I haven't really felt it in weeks. Turns out that working out the muscles opposite to the ones you think is the key (therapy putty did nothing).