> on both US QWERTY and Colemak when you constantly type [];:{}| and so on, your pinky has to reach over to do it. At least for me that meant contorting my hand a bit to reach over. On my split keyboard all the symbols are behind a layer on the home row, and I barely use the pinky for anything, which fixes the issue.

On a completely standard rectangular-block keyboard, I don't use pinkies to type. Actually, I do use my left pinky to hit left shift. But that's it.