And I might not have been clear enough on acceleration. I meant you might be able to construct a device capable of FTL transport, but it might be far harder to traditionally accelerate this entire device to high speed. The FTL isn't moot, but if your FTL is only 5c and you can't accelerate your turned-off FTL device faster than .1c you're not going to make any loops with it.
In other words, in this scenario, there isn't a preferred frame of reference per-se, but there's no way for such a large and complex construct as an FTL device to get far enough away from the galaxies' default reference frame.
Personally, I think that supporters of FTL should stick with subspace and run with it. And, hey, the author of the FTL faq even wrote a whole subspace faq too.