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Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by jayd16 on Thursday October 02, 2025 @04:43PM (#45455315)
I do wonder how the psychology of humanity will change once you can't wait for someone to die, and conversely, you can't expect to die before consequences catch up to you.
Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by SequoiaHope on Thursday October 02, 2025 @04:59PM (#45455491)
Without going in to spoilers, the recent season of the Revolutions podcast about a future fictional revolution on Mars touches on this a fair bit. Someone about to die seizes power for himself, but no one cares much because he was already in charge and extending his reign a few more years till he dies was no big deal, until he extends his life and lives another 75 years.
Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by observationist on Thursday October 02, 2025 @06:30PM (#45456374)
"Putin Eternal", or something like that. Ironically, the technology will probably lead to faster, worse fates for many like that than might have been the case if they'd just left it alone.
Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by JumpCrisscross on Thursday October 02, 2025 @04:44PM (#45455322)
> once you can't wait for someone to die, and consequently, you can't expect to die before consequences catch up to you

People will still die, even in a world without ageing, which this treatment doesn't promise.

Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by Retric on Thursday October 02, 2025 @05:48PM (#45456013)
The risk of death per year increasing with number of years lived is aging.

Without that people have lived longer are more likely to have lower risks of death per year. And thus older people in such a society would on average live longer.

Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by dandellion on Thursday October 02, 2025 @06:06PM (#45456187)
Unless it also cures cancer a more likely outcome is that people who get the treatment will just stay young until they get cancer and die. Also, as I understand it cancer also slows down in old age, so staying younger could mean faster cancers possibly negating some of the gains from the decreased aging.
Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by Retric on Thursday October 02, 2025 @06:09PM (#45456207)
Aging is more than just looking old.

If someone has an increased risk of death per year from cancer or whatever because something is failing over time they are still aging.

If the rate per year stays the same IE being 20 or 20,000 has no impact on your risks of cancer each year then someone that’s 20,000 likely takes very few other risks and is more likely to live another 20,000 years than the random 20 year old.

Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by MagicMoonlight on Friday October 03, 2025 @01:11AM (#45459219)
Cancer is primarily caused by aging, so in this world there likely wouldn’t be much cancer outside of the deliberate cancers caused by things like smoking
Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by jibal on Saturday October 04, 2025 @06:05AM (#45472181)
This is grossly wrong. "anti-aging" treatments won't reduce people's ages and won't undo epigenetic damage. And while age is the single strongest risk factor for cancer, it isn't the "primary cause", and there are numerous non-age-related causes of cancer.
Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by Retric on Saturday October 04, 2025 @07:47PM (#45477758)
Bad “anti-aging” treatments definitely won’t do it, but they also won’t provide indefinite lifespans.

> it isn't the "primary cause

Only if you’re using an inaccurate definition of aging. If everyone over 20 should have the same risk of cancer as 20 years olds the total number of cancers would drop by more than half.

Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by jibal on Sunday October 05, 2025 @03:34AM (#45479605)
P.S. The response is incoherent. Talk about "inaccurate definition" ... someone has an inaccurate definition of "cause".
Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by jibal on Monday October 06, 2025 @05:20AM (#45489409)
Most of humanity will die in this century as a consequence of global warming, a subject that barely gets a mention at this site. There was a window of hope, but the Trump administration's policies have closed it.
Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by heavyset_go on Thursday October 02, 2025 @05:34PM (#45455883)
The Altered Carbon universe is a manifestation of this.
Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by ugh123 on Thursday October 02, 2025 @05:41PM (#45455953)
I'm certain, at some point in the not so distant future, Neuralink will create an arm of the company to build "sleeves".
Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by jhallenworld on Thursday October 02, 2025 @07:07PM (#45456653)
Altered Carbon used alien magic, the way this works in the real world will be far worse: Brain transplants. First, many poor people will need to be used as guinea pigs (a la the Sun King's anal fistula). Then once it works.. well some strapping young man (or woman!) will have to "volunteer" their body to host Elon's brain.
Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by PoorlyNamed on Thursday October 02, 2025 @07:13PM (#45456696)
Get Out.
Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by selcuka on Thursday October 02, 2025 @08:37PM (#45457354)
They don't need a volunteer. They can clone themselves when they are, say, 30 year old and they will have a 100% compatible, 20 year old donor who has spent their life in suspended animation when the original is 50.
Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by jhallenworld on Thursday October 02, 2025 @08:50PM (#45457450)
No that won't do. You need someone else to prepare the body: you know... rigorous workouts for strength and physique. Ideally the person is an excellent cage fighter and has the reflexes of a top-tier video gamer.
Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by Terr_ on Friday October 03, 2025 @03:15AM (#45459978)
The practice of illegal clone brain transplants figures in some of the Vorkosigan series books: The clone-children of various customers are raised in cohorts, and taught little while enduring years of strictly controlled diets, cosmetic surgeries, and exercise regimes.

Then, one day, the are told their important and distant "parents" are finally arriving to bring them away to their new life...

Anyway, the point is that any aging wealthy pedicidal murderers are also gonna insist the body is perfect before they move in, meaning some other brain is going to be doing the work.

Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by falcor84 on Friday October 03, 2025 @04:46AM (#45460589)
Thanks for bringing that up, it's probably time got for me to reread the Vorkosigan Saga.

And you also reminded me of the flawed but moving film "Never Let Me Go" from 2010 about a more present version of this. Oh, and there's also Michael Bay's "The Island".

Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by ben_w on Friday October 03, 2025 @03:59AM (#45460276)
All options are too far away to predict which will come first, or with what side effects.

(In practice, almost everything over 5 years away, even when already in early human trials, has this property; the only reason the Covid vaccines happened faster is that everyone was willing to throw unlimited resources at the problem and do simultaneous tests on all candidates, and in a pipeline, rather than cost-efficiently and slowly like everything else has been).

In-vitro tissue culture is already a thing (including brain organoids, if you want a brain to control a robot: https://en.wikipedia.org/wiki/Cerebral_organoid), as is 3D bio-printing.

IIRC, there's no current way to scan even a single living synapse/synaptic cleft/dendrite combination to read out the corresponding connection strengths, let alone for the whole brain, so we can't yet scan a brain — but if we could do that, writing it back to a fresh blank one currently seems(!) like the easy part, as neurons change shape and grow in response to electrical gradients.

Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by Terr_ on Friday October 03, 2025 @04:46AM (#45460595)
One non-measuring idea is to gradually replace portions of the brain with artificial blanks, relying on some sort of holistic (or holographic) redundancy where the "damage" is repaired by neighbors.

This, er, Brain of Theseus would retain operational patterns even if the individual cells have been replaced.

A variation on that would be too do it stochastically, constantly substituting a miniscule percentage of cells evenly across the entire brain.

Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by CyberDildonics on Friday October 03, 2025 @09:57AM (#45463100)
the Sun King's anal fistula

This thread is about stem cells in monkeys.

Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by aspenmayer on Thursday October 02, 2025 @05:50PM (#45456034)
Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by bix6 on Thursday October 02, 2025 @04:52PM (#45455408)
Consequences seem to not matter so we’ll just get a bunch of meths like from altered carbon.
Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by roxolotl on Thursday October 02, 2025 @07:01PM (#45456612)
If you’re curious about fiction which thinks about this there’s Altered Carbon which is “what if the rich assholes can live forever” and there’s The Postmortal where all assholes get to live forever.
Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by throw__away7391 on Thursday October 02, 2025 @07:40PM (#45456900)
As I have gotten older I've slowly realized that waiting for people to die takes a long, long time, and no longer regard it as a good strategy.
Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by ian-g on Thursday October 02, 2025 @07:51PM (#45457000)
Unfortunately seems to only be the case in aggregate
Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by michaelsbradley on Thursday October 02, 2025 @05:09PM (#45455595)
cf. Palpatine
Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by positron26 on Thursday October 02, 2025 @11:08PM (#45458520)
I'm not an expert in psychology, but within a fixed population window, the murder rate will only go up unless there is a limited supply of those who murderers want to murder or unless murderers tend to prefer murdering other murderers, perhaps due to the change in game theory creating a new incentive. As humans would begin to live ever increasingly far away, we may approach a "murder death" condition where no new murders are possible. I will leave alone those who played Among Us until their numbers diminish and there is a better chance of reaching an early asymptote.
Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by ben_w on Friday October 03, 2025 @03:14AM (#45459973)
> you can't expect to die before consequences catch up to you.

Many of the worst people in humanity, seem(ed) to act like they thought they were immortal.

Even being grazed by a bullet didn't stop Trump praising the second amendment.

(Though I say that as a non-American, and someone for whom the 2nd was part of why I never even considered attempting to migrate to the US; I do recognise the language used to support it as a quasi-religious badge of identity, i.e. hard to shake).

Re:Anti-Aging Breakthrough: Stem Cells Reverse Signs of Agin... by xethos on Friday October 03, 2025 @03:36AM (#45460133)
> Even being grazed by a bullet didn't stop Trump praising the second amendment.

This at least gives the semblance of Trump having and sticking to a set of principles (though I suspect it's more to do with what his supporters would accept)