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Re:Review of Anti-Aging Drugs by cactusplant7374 on Sunday August 17, 2025 @02:57PM (#44933963)
Rapamycin modulates the immune system. I get that he's probably consulting a doctor but can you imagine taking this risk during a pandemic or even in older age? It makes me uncomfortable to play around with these very powerful drugs.
Re:Review of Anti-Aging Drugs by YZF on Sunday August 17, 2025 @03:06PM (#44934030)
The dosage for longevity is supposed to be low enough that this risk is minimized. Lots of things you do modulate your immune system (including e.g. exercise). It's a risk/reward thing, every time you get into your car you're also taking a longevity risk.

I think there are some proper human trials happening but the jury is still out.

Re:Review of Anti-Aging Drugs by cactusplant7374 on Sunday August 17, 2025 @03:30PM (#44934210)
> I think there are some proper human trials happening but the jury is still out.

That's exactly my point. No one really knows the risk that they are taking.

Re:Review of Anti-Aging Drugs by lokrian on Sunday August 17, 2025 @04:04PM (#44934479)
People are still getting nerve damage from too much vitamin B6 in energy drinks and vitamin supplements, and that's a well known and widely taken vitamin. The idea that you can take experimental drugs your entire life at little risk is optimistic.
Re:Review of Anti-Aging Drugs by cactusplant7374 on Monday August 18, 2025 @04:11PM (#44944767)
I had no idea. At points in my life I consumed a lot of nutritional yeast.
Re:Review of Anti-Aging Drugs by rscho on Sunday August 17, 2025 @03:41PM (#44934313)
Surprisingly, many people seem to think that pushing a few random pills into a machine optimized over some million years of evolution will tune it so it works better. Go figure...
Re:Review of Anti-Aging Drugs by Etheryte on Sunday August 17, 2025 @03:57PM (#44934435)
It works for the majority of modern medicine, so it's not all that black and white.
Re:Review of Anti-Aging Drugs by rscho on Sunday August 17, 2025 @04:08PM (#44934515)
Yes, although even for modern medicine curative and preventative strategies are very distinct. Sure, they'll give you pills to compensate for a problem you already have. But there are few meds that protect you against stuff you'll maybe catch in the future. Vaccines and antibiotics are obvious examples, but I'm not aware of many others. The rest of preventative strategies overwhelmingly consists in correcting deficits or excesses (calories, vitamins, sleep, exercise etc.)
Re:Review of Anti-Aging Drugs by jordanb on Sunday August 17, 2025 @03:00PM (#44933982)
These roads people go down always arrive at eating collidal silver...
Re:Review of Anti-Aging Drugs by MarcelOlsz on Sunday August 17, 2025 @03:07PM (#44934031)
Get with the times, methylene blue is the new it girl.
Re:Review of Anti-Aging Drugs by malfist on Sunday August 17, 2025 @06:06PM (#44935338)
As a party trick, it'll make people pee blue. But don't do this, it isn't safe. Especially without consent