Can you go into detail about these substances?

Maybe the fiber helps?

Fiber is great for gut health but it's actually works against nutrient absorption. Increasing fiber intake requires increasing intake of certain vitamins, possibly with supplementation.

It's better to eat things in moderation and know what antinutrients are in what foods. There are tradeoffs.

Exactly. Fiber sucks up some nutrients so they are either pooped out due to limited digestibility of the colon, or get consumed by gut bacteria.

Fruits have fiber, polyphenols, and rare sugars. I don't know which of these helps control the risk.

You are invoking a fallacy known as 'begging the question' in that statement because you never establish that any of those things control the risk, just that they exist in fruit.

No, I'm sorry but that's not correct. "Natural" is a meaningless health and wellness buzzword that handwaves away the details that each food comes with benefits and disadvantages. There are variable amounts of anti-nutrients almost every "natural" ingredient, some of which we process or cook to lessen them.

Indigenous people processed acorns to remove tanins.

Kidney beans (and many other legumes to variably lesser degree) naturally contain phytohaemagglutinins (PHA-E) which cause red blood cells to clump together. These can be reduces several orders of magnitude by repeated cooking, washing, and draining.

Men shouldn't eat too much soy or chia seeds. Small amounts of chia seeds are fine.

Most adults are lactose intolerant unless they have lactase persistence genes.

Spinach, pepper (the spice kind), rhubarb, almonds, and more contain oxalate that can lead to kidney stone formation. Excess vitamin C does also. Increasing citrate intake helps prevent calcium kidney stone formation, but doesn't help with oxalate kidney stones as much.

The list of antinutrients is long. Don't overdo eating one "natural" ingredient or another because that's the greatest risk of becoming a Chubbyemu video subject.

Exactly. Nature is there mostly to kill you, that is only natural, and thinking otherwise is basically resorting to divine. No living being wants to be food. There can be symbiotic behavior and plants can produce certain chemicals that attract animals that do some things for them like helping reproduction, but its huge stretch to claim that evolution optimizes for health by proxy. Most off beneficial effects of plant chemicals are due to shared pathways and hormesis.

I was referring to the fruits which may contain a tiny amount of erythritol, not to your random list.