>Strangely it seems to me that a lot of effort is going more into being able to simulate full cells that contain unknown mechanisms, rather than trying to use the capabilities to create hypothesis to uncover the unknown mechanisms. Yes, that probably expedites the path towards simulating much bigger human cells, but ultimately still leaves us in the dark on most fronts.

Seems the result of this general trend in science towards brute prediction and abandoning the goal of explanation or understanding.