It might. Going faster likely increases wear on moving parts, which would presumably result in longer ground times for more frequent maintenance?

Sure it does.

If you have demand for 10,000 passengers to be transported on a route daily, and a plane carries 200 people, you would need 50 trips. If the round trip is 4 hours, you could do 6 trips per plane and you'd need 9 planes to service the route.

If the round trip time is 8 hours, you could only do 3 trips per day and you'd need 17 planes.