Factorio is not a puzzle game. You can get puzzle like gameplay if, for example, you are on a map with heavily restricted space, or are trying to micro-optimize something. But that is analogouse to code-golf or microoptimizations in programming, which are fairly puzzle like.

For typical gameplay, the only puzzles you run into are the ones you build yourself into. The name of game is to design your factory in a modular and extensible way so that you do not build yourself into a puzzle.