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A comment on Strep A kills half a million per year; why don't we have a vaccine?.

Re:Strep A kills half a million per year; why don't we have ... by hypercube33 on Saturday October 19, 2024 @02:20AM (#41885992)
What about bacteria phages for strep? If I'm not mistaken and I really could be but I thought we use them to keep some meats fresh? I didn't dig into this further many years ago but I also haven't seen anything new either beyond a paper suggesting their research.

Antibiotics come up here a lot and other places in discussion due to their (possibly) bad side effects or immunity with excessive use.

I think someone else here pointed out that it's tricky to make an immune response have the desired outcome and no undesired ones so a vaccine may not be the right hammer for this nail.

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Re:Strep A kills half a million per year; why don't we have ... by Fomite on Saturday October 19, 2024 @02:25AM (#41886019)
HN tends to love phage, but for this application, it's not a great one, because the infrastructure required to safely do phage prep greatly exceeds what you need even for complex vaccines.
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Re:Strep A kills half a million per year; why don't we have ... by cenamus on Saturday October 19, 2024 @03:50AM (#41886343)
Especially for diseases that can be cured with regular antibiotics, but aren't due to different reasons
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Re:Strep A kills half a million per year; why don't we have ... by OutOfHere on Monday October 21, 2024 @01:24PM (#41906272)
The development of phages has thus far made more sense for resistant infections. Perhaps phages could also help patients with chronic lung infections. For strep there isn't much motivation even if it's theoretically desirable.
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