The issue is that these are near monopolies, so the market isn't efficient.
In other words, if those companies didn't have monopoly power, other businesses (or non-commercial entities) might be able to afford to hire some of these people as well, which might be beneficial overall for innovation.
That's the economic argument and it's pretty clean imo.
But as far as I'm concerned personally, I would really prefer to live in a world in which smart people work on human flourishing... rather than whatever that is.
From the economics perspective, something being Monopoly doesn't mean it's inefficient.
Depending on the situation, they can be far more efficient then diverse companies, or much less
From an economics perspective, if there is a monopoly, there is no free market, so you can't rely on the market for efficiency. A monopoly can be efficient, but it can also be arbitrarily inefficient and still keep its position.
I was trying to make the point that monopoly isnt defined by inefficiency, either by the technical definition or the colloquial one.
Rality is complex, and few monopolies can be arbitrarily inefficient. I think this is where a lot of the public confusion about monopiles comes from.
If you have the only grocery store or gas station in town, it might seem like there is a monopoly. There is probably a wide leeway to raise prices or be inefficient, but not without limit or else someone would compete.
If Amazon, Google, or whomever 10X'd their prices, competitors would arise.
That's the reason why quantum computing and projects of this type would not exist if you didn't have behemoth companies with extra cash lying around.
You might think it is is inefficient to have a miracle cure for cancer tied up on patent for 20 years, but what are you comparing it to.
A rational company would lower the price if that broadened the market and netted more profit by volume. Drugs aren't Veblen goods.
The impetus for jacking up drug prices is that the market is captive, and those who need the drug will obtain it. That and insurance/government is often the payor.
It's the same reason SAAS took off so much. If you sell the product and consumers are (relatively) happy, now what? They might come back and buy another version in 5-10 years, but how do you generate enough cash flow between now and then to stay afloat?
The time value of money means you want to sell every dose as soon as possible. with a 10% annual return, $1,000 today is better than $2,600 in 10 years.
Additionally, each day that passes, someone else can come in and outperform you or undercut your price.
I see the sentiment a lot, but it strikes me as reality denialism. People are willing to pay for one thing but not the other.