He also doesn't understand what computation is, even though he often makes confident statements about it. He thinks computation is a subjective process, that something only counts as a computation if someone interprets it as such, which is simply wrong, not a debatable topic. And this is the core of one of his other arguments about why consciousness can't be a computational process.
Still, the laws of physics could be anything and it wouldn't matter for this question. The only relevant question is whether our brains are computers, regardless of how the physics work at the lowest level. After all, we have clear proof that you can make computers on the existing laws of physics (I'm typing this reply on one!), so all we need to know is whether our brains are bio-chemical computers. Neuroscience is nowhere near a level where it can answer this, but it at least remains a plausible explanation. After all, we humans can't compute any non-computable function, or at least none that we know of (the Church-Turing thesis).