I am not an artist and also dislike multiple monitors, though I will employ two of them on occasion.
My reasons are:
If the window and application management doesn't suck, one display is all one needs.
With cheap multiple displays and touch devices came an ongoing enshitification of app and window management. (And usually dumber focus rules)
Having to turn my head x times a day sucks.
Once it works, Linux is more reliable than Windows. And virtual desktops have always worked better on Linux than on Windows. So I disagree with you on that front.
* In my case, this means I had to get an Anker HDMI adapter, instead of any random brand.
Maybe as long as you don't need working fractional scaling with different DPI monitors, which is nothing fancy now.
There's little things too, like some people using gaming peripherals (multi-button MMO mice and left hand controllers, etc.) for editing, which might not be compatible with OSX.
And also, if you're mucking around with two 32 inch 4k monitors and a 16 inch Wacom it might start to feel a little ridiculous trying to save space with a Mac Pro.