Ketamine's effect on depression may hinge on hope

Re:Ketamine's effect on depression may hinge on hope by omginternets on Friday October 20, 2023 @03:24PM (#37960376)

>And in case of some substances like drugs if you reduce dosage or adjust protocol so that trip doesn't happen means that you also got rid of any significant effect it might have on the brain.

We agree. My point is that the evidence seems to be going in the direction of:

1. removing transcendence removes part of the benefit; and,

2. to complicate matters, many protocols fail to properly control for transcendent experience because a lot of control groups are placed in a quiet room, free of distraction, and invited to ponder life.

We're both materialists. Mine is a materialist position.

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Re:Ketamine's effect on depression may hinge on hope by scotty79 on Friday October 20, 2023 @05:04PM (#37961499)

> We're both materialists. Mine is a materialist position.

I'm not quite sure about you because you are using words like transcendence. ;-) In my view the deep experience of the trip, what you call transcendence, is just another hallucination, just hallucination of meaning and understanding instead of simple images, sounds or sensations.

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Re:Ketamine's effect on depression may hinge on hope by omginternets on Saturday October 21, 2023 @12:25PM (#37968178)

Transcendence is a qualia of experience; it says nothing about whether an immaterial substance is required to experience it.

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