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Re:How Many Microbes Does It Take to Make You Sick? by Sakos on Sunday October 01, 2023 @01:11PM (#37728063)
This is one of the reasons why masks are so important and why they don't need to be 100% effective. Just reducing the amount of viral load could turn a serious infection into something you might barely notice.

edit: Imagine this being controversial. I didn't realize there were Covid deniers and skeptics here, because what I've stated is completely within established science.

Re:How Many Microbes Does It Take to Make You Sick? by pton_xd on Sunday October 01, 2023 @01:39PM (#37728385)
> This is one of the reasons why masks are so important and why they don't need to be 100% effective. Just reducing the amount of viral load could turn a serious infection into something you might barely notice.

It would be nice to have some numbers to back this up. Lets suppose the "viral load" to acquire a Covid infection is 18 particles, the same as norovirus detailed in the article. And let's say you're exposed to hundreds of thousands of viral particles every minute you spend near a sick person [1]. If a mask reduces your viral load by 50%, is that a worthwile method of avoiding infection? It is not.

[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598485/

Re:How Many Microbes Does It Take to Make You Sick? by sfblah on Sunday October 01, 2023 @01:48PM (#37728460)
There are good studies on viral load reduction from masking with flu viruses from before 2020. After 2020 the topic became politicized so the studies are probably unreliable.
Re:How Many Microbes Does It Take to Make You Sick? by MrLeap on Sunday October 01, 2023 @01:48PM (#37728463)
The assertion is that if you dump a gooey grey gallon of pure covid on someone, their symptoms will be more severe than if they only get 18 virions. Do you suppose that wouldn't be the case?
Re:How Many Microbes Does It Take to Make You Sick? by Jabbles on Sunday October 01, 2023 @01:59PM (#37728594)
From that link:

Our simulation also shows that wearing a mask can effectively reduce the spread of the viruses.

Re:How Many Microbes Does It Take to Make You Sick? by pton_xd on Sunday October 01, 2023 @02:01PM (#37728619)
Sure, by some metric masks are very effective at stopping viral particles. After all, in my example the mask will stop tens of thousands of viral particles from reaching you every minute.

Another metric is, will that stop you from getting sick? The threshhold is only 18 particles!

Re:How Many Microbes Does It Take to Make You Sick? by epivosism on Sunday October 01, 2023 @02:34PM (#37728978)
All the factors you mention are scalar. You can wear 0,1,2,3 masks. You can be 1,2,3,10,20 feet away from the person for 0,1,5,10 minutes. I can come up with any number of such factors involving wind, lifetime of virus, the person's shedding rate, etc.

Given that, there will always be a border at which having an additional 50% coverage is useful. Where the actual line is, we don't know. But as long as protection is monotonic in the factors above, it's always valuable to have more protection, which implies even <100% effective masks are useful.

Trivial proof: Imagine someone with literally 10k masks all around them. You have to admit this is more safe than 1 mask. QED. You can call in meta factors like "in reality nothing matters" but you're arguing by consequences then, not actually disagreeing with the facts, just claiming they don't matter.

Re:How Many Microbes Does It Take to Make You Sick? by elsonrodriguez on Sunday October 01, 2023 @01:35PM (#37728335)
The exploration of truth is anathema to those who claim to already have the truth.
Re:How Many Microbes Does It Take to Make You Sick? by sfblah on Sunday October 01, 2023 @01:46PM (#37728448)
What you said isn’t controversial. It’s definitely right.

The issue with masks is one side started treating them like a talisman that makes infection impossible, which provoked the other side to say they do nothing.

On a population level, masks are probably close to ineffective against a viral pathogen. You can read the relevant Cochrane review to see that.

On an individual level they obviously do something, but you have to consider other factors as well, such as level/frequency of exposure and the like. Studies from prior to the pandemic suggested that a perfectly fitted N95 mask dramatically reduced flu virus penetration. For a more normally worn N95 the reduction was about 70%. For a surgical mask it was essentially nil. Importantly, a perfectly fitted mask required essentially gluing it to the face of a mannequin.

Final point is, with an intervention whose impact is measurable but imperfect, you have to consider the side effects. I personally know several friends of my teenage kids who now have odd (to me at least) social phobias for which the only “cure” is to wear masks everywhere. Just last weekend I was talking to a friend of my daughter who wears masks everywhere except indoors.

Re:How Many Microbes Does It Take to Make You Sick? by AnthonBerg on Sunday October 01, 2023 @02:41PM (#37729054)
The un-cited Cochrane review in question does not say that.

From Cochrane.org:

Statement on 'Physical interventions to interrupt or reduce ... - Cochrane

Mar 10, 2023

Many commentators have claimed that a recently-updated Cochrane Review shows that 'masks don't work', which is an inaccurate and misleading interpretation. It would be accurate to say that the review examined whether interventions to promote mask wearing help to slow the spread of respiratory viruses, and that the results were inconclusive.

Repeating the important part:

the review examined whether interventions to promote mask wearing help to slow the spread of respiratory viruses

Conversely, here’s a good study that shows that consistent use of FFP3 respirator masks drastically reduced transmission among workers on a hospital ward: https://elifesciences.org/articles/71131

Note that the study only had the workers wearing FFP3 masks on shifts, and community transmission was high at the time. Therefore the study “leaked” and good masks work better than the numbers in the study might seem to indicate. Face-fitting masks do work, and very well. Of course they do. It’s all very clear if you dig into the aerosol physics.

Re:How Many Microbes Does It Take to Make You Sick? by sokoloff on Sunday October 01, 2023 @03:32PM (#37729647)
It looks like FFP3 are analogous to N99 masks.

A mask mandate that permits "wrap a piece of T-shirt over your mouth, some of the time, sometimes even covering your nose" (which is not far from what I saw for much of 2020) is, unsurprisingly, going to be more effective at ensuring grudging compliance with a mandate than it is to reduce the spread of an airborne virus.

Re:How Many Microbes Does It Take to Make You Sick? by sfblah on Sunday October 01, 2023 @03:57PM (#37729952)
This is the problem with mask absolutists. They take data from masks that are super effective (hospital setting, correct usage, basically gluing the mask to your face) and extrapolate it to some guy on the subway with a cloth mask. It’s a bad way to make public policy, and I don’t really understand the motivation behind it.
Re:How Many Microbes Does It Take to Make You Sick? by AnthonBerg on Sunday October 01, 2023 @05:05PM (#37730776)
I am not a mask absolutist.

Close family is at risk of severe illness or death from COVID. We provide for a small child. We do not have much margin.

I’d like to ask you to imagine the social repercussions of masking. It’s hard. I do not want to be weird. I do not want to be an outcast, practically speaking. I don’t want to wear a mask.

I just don’t have any margin in the other direction.

Also:

What is it about a hospital setting that makes a given type of mask more effective?

Answer: Nothing.

Hospitals are places where it’s easier to run a trial, and where it’s harder to avoid infection.

Face-fitting masks do not require glue. Fitting a mask isn’t that hard.

Cloth masks don’t work and never did.

The objective is to not die or be maimed by a virulent pathogen, or rather: to have the option. Clarity on effective means for those who want it. I want effective means because I need them. The objective is not social classification of mask wearers or categorization of discussion types or labeling people as cartoons.

The objective is clear information as input into serious personal decision-making. The guy on the subway is not in scope.

Re:How Many Microbes Does It Take to Make You Sick? by sokoloff on Sunday October 01, 2023 @05:10PM (#37730841)
I think hospital workers experience with wearing masks (and the resulting "they have chosen a mask size and from experience have adjusted the mask to make it comfortable and effective") and the ability for the hospital to prohibit facial hair in their workers that's incompatible with effective mask use are key differences between hospital staff and Joe/Jane Public on the streets.

In terms of being weird: there are enough people wearing masks and most people literally care more about what they're going to have for dinner than whether or not you're wearing a mask. If a mask helps your family, don't worry about the epsilon weird aspect (as I'm sure you have already calculated).

Re:How Many Microbes Does It Take to Make You Sick? by AnthonBerg on Sunday October 01, 2023 @05:41PM (#37731151)
Well said. Thank you.

I think I can also pretty decisively say that hospital purchasing optimizations give face-fitting masks a bad rap. The FFP2 masks that hospital staff wear here are cheap and very uncomfortable. This bleeds into society as a negative view.

Re:How Many Microbes Does It Take to Make You Sick? by sfblah on Sunday October 01, 2023 @06:06PM (#37731374)
Occam's razor here is that your interest in masks is a mental illness, and not because someone in your family is so immunocompromised or whatever that the mask is standing between that person and certain death. Is it possible that the latter is the case? Maybe. But in my view almost all cases of people stubbornly wearing masks are just psychiatric in nature.

I know my comment will just make you angry, because "you're different". But, maybe someone else will see it and consider their psychological state on this topic.

Re:How Many Microbes Does It Take to Make You Sick? by AnthonBerg on Sunday October 01, 2023 @06:24PM (#37731559)
I wish upon you severe illness and the humility to deal with the repercussions to your worldview, and happiness.

I wish for your life to be long and healthy; and the lives of your loved ones too. And in that, let me give you advice to trade for your judgement of my place in life and my actions and sacrifices and loss. The advice is this:

Read. The academic. Literature.

Re:How Many Microbes Does It Take to Make You Sick? by kbelder on Monday October 02, 2023 @12:30PM (#37740496)
I know a family who still wears masks in public because their daughter is very sick, very weak, and they don't want to risk her getting covid. Perfectly sensible. I also know people who wear masks in public because they're a little nuts... just can't let go, or politically or psychologically hung up.

So what can you say? You see a stranger wearing a mask, you don't know if it's for a good reason or not. Probably the odds are that it's an emotional or psychological hangup, but it may be for a really good reason. So you need to just shrug and let people do what they think best for themselves. They're the ones responsible for themselves.

Re:How Many Microbes Does It Take to Make You Sick? by AnthonBerg on Sunday October 01, 2023 @04:58PM (#37730698)
Precisely.
Re:How Many Microbes Does It Take to Make You Sick? by sfblah on Sunday October 01, 2023 @03:59PM (#37729969)
I would encourage readers to read the “Main results” section of the review for themselves. It takes under 5 minutes. Don’t trust a commenter on any online forum on this topic (myself included), as it’s completely politicized.
Re:How Many Microbes Does It Take to Make You Sick? by AnthonBerg on Sunday October 01, 2023 @04:57PM (#37730685)
Also read the studies themselves.

And the criticism of the Cochrane-method review.

And the studies not cited.

As well as the studies on the mechanics of transmission.

Re:How Many Microbes Does It Take to Make You Sick? by sfblah on Sunday October 01, 2023 @06:08PM (#37731387)
I think people can rely on the authors to put the main results in the "Main results" section. What they can't rely on is potential nutters in Internet forums.
Re:How Many Microbes Does It Take to Make You Sick? by rootusrootus on Sunday October 01, 2023 @02:25PM (#37728870)
> For a surgical mask it was essentially nil.

Is the surgeon wearing a mask to protect himself from me, or to protect me from him?

Re:How Many Microbes Does It Take to Make You Sick? by AnthonBerg on Sunday October 01, 2023 @02:43PM (#37729067)
The surgeon is wearing it because of an old, old misinterpretation of reality.

This article is factually accurate: https://www.wired.com/story/the-teeny-tiny-scientific-screwu...

Re:How Many Microbes Does It Take to Make You Sick? by stopping on Sunday October 01, 2023 @03:13PM (#37729444)
Your assessment is a non-sequitur to the article.

Surgeons wear masks to protect the patient, because masks are very effective at trapping both droplets and aerosols that are emitted from the wearer. They are not designed to protect the user from lingering aerosols as masks are too loose to form a good seal, so most air breathed in simply enters from around the sides of the mask.

Re:How Many Microbes Does It Take to Make You Sick? by AnthonBerg on Sunday October 01, 2023 @04:57PM (#37730679)
Surgical masks defined as the ones that gape at the sides are comparatively ineffective at stopping aerosolized particles.

The idea that ballistic droplets are the primary means of infection is the old, old misunderstanding.

If we compare the objective of preventing transmission of pathogens from surgeon to patient to the objective of covering nudity, surgical masks are as effective as shorts.

Seeing as the objective is the objective, the ends should define the means. Therefore it is clear that any use of surgical masks is a fundamental and entrenched misunderstanding.

Re:How Many Microbes Does It Take to Make You Sick? by stopping on Sunday October 01, 2023 @05:48PM (#37731215)
There are many studies which show that surgical masks are quite good at stopping a majority of expelled particles, even those well within the aerosolized size regime:

Surgical masks reduce outward aerosol-sized particles by at least 74%: https://www.nature.com/articles/s41598-020-72798-7

Surgical masks reduce outward COVID viral transmission by 73%, and viral RNA by 58%: https://journals.asm.org/doi/10.1128/msphere.00637-20

Outward filtering efficiency above 50% is certainly worth it compared to the cost of a surgeon wearing a mask. It's arguably worth it even at much lower efficiencies.

If you read my comment, you'll notice I'm not disagreeing on the aerosol/droplet size boundary. I'm arguing against the apparent subtext of your comment, which seems to indicate that surgical masks aren't effective at protecting patients.

Re:How Many Microbes Does It Take to Make You Sick? by AnthonBerg on Sunday October 01, 2023 @06:00PM (#37731326)
Well said, thank you. Sincerely!

I’d like to reiterate my analogy of the shorts :)

Not least due to the subtle knock-on effects: surgical masks cast a fog on public awareness of face-fitting masks, which are superior in all respects (including comfort, which – case in point – came as a surprise when I tried one).

—

The effectiveness of face-fitting masks is so much greater that I honestly regard the use of surgical masks as morally indefensible.

Re:How Many Microbes Does It Take to Make You Sick? by msie on Sunday October 01, 2023 @02:05PM (#37728652)
That Cochrane review is faulty and one of the co-authors (Tom Jefferson) "works for the Brownstone Institute, a Covid-19 misinformation group that is powered by dark money."

https://www.theguardian.com/commentisfree/2023/feb/27/dont-b...

Re:How Many Microbes Does It Take to Make You Sick? by jimwhite42 on Sunday October 01, 2023 @02:23PM (#37728834)
As far as I can tell, the issue is people misrepresenting what the review says, not that the review is faulty.

The review concludes that we have evidence that masks are effective, but the set of papers reviewed cannot be used to conclude we know the level of effectiveness enough to make accurate judgements on tradeoffs in many of the kinds of situations where people were asked to wear masks in the pandemic. So we don't know enough yet.

I read a bunch of the criticisms of this paper and criticism of the anti-maskers misrepresentation of what it said, and none of the ones I found suggested that there were missed papers which provide the precision the review didn't find.

The Guardian article is a mixed bag in my opinion. It tries to get around the idea that we really need more research, it confuses a lot of things.

(BTW, I am not an anti masker, I wore a mask, I find people who whine about wearing them to be a bit pathetic most of the time.)

Re:How Many Microbes Does It Take to Make You Sick? by maxerickson on Sunday October 01, 2023 @03:08PM (#37729382)
which provoked the other side to say they do nothing.

This somewhat excuses their reactionary stupidity. Like they weren't "provoked", the use of masks wasn't directed at them.

Re:How Many Microbes Does It Take to Make You Sick? by sfblah on Sunday October 01, 2023 @03:44PM (#37729810)
Where I live, in Alameda County, California, masks were required outdoors if you were within 30 feet of another person. This ridiculous policy lasted about a year and provoked all kinds of altercations. It also made exercise, a key way to say fit, much more difficult. So, in this case I would argue mask use was in fact “directed at” people.
Re:How Many Microbes Does It Take to Make You Sick? by maxerickson on Sunday October 01, 2023 @04:07PM (#37730048)
When you say that, you are saying that the policy was put in place in bad faith in order to inconvenience the people that didn't like it. The argument is more ridiculous than the policy.

Here there was never an outdoor mask policy, so I didn't ever have a chance to evaluate my reaction to such a thing. There was apparently a policy banning stores like Walmart from selling seeds (which I interpreted as bureaucratic friction rather than intention, something that was born out relatively quickly in practice, and never in the minds of the reactionaries).

Re:How Many Microbes Does It Take to Make You Sick? by sfblah on Sunday October 01, 2023 @04:23PM (#37730250)
There’s a fine line between a policy being intended to harm and just being stupid. Regardless of the rationale, I was just trying to demonstrate how such policies were in fact weaponized.

You can do some reading about the Bay Area and debates over whether government policies are in bad faith. I think it’s at least arguable that some are in fact in bad faith (meaning, no one really thinks they’ll serve any public purpose other than punishing groups of people).

Re:How Many Microbes Does It Take to Make You Sick? by jeffbee on Sunday October 01, 2023 @05:26PM (#37731017)
Nothing was "weaponized" by this order, which 100% of people ignored.
Re:How Many Microbes Does It Take to Make You Sick? by sfblah on Sunday October 01, 2023 @06:00PM (#37731325)
I wish what you were saying were true, but it just isn't. I'm a fairly serious runner -- 40-60 miles per week typically. The amount of nonsense I experienced during that year might surprise you. Dozens of different times I was yelled at on trails, in the street, etc. because I was "too close". I was threatened with violence multiple times. This was all in the context of trying as hard as I could in all cases to stay as far from people as possible -- 10 feet minimum -- and to pass them as expeditiously as I could. I avoided narrow trails in parks completely, etc. People went insane, and it was absolutely due to this policy.
Re:How Many Microbes Does It Take to Make You Sick? by verve_rat on Monday October 02, 2023 @02:54AM (#37734779)
Yes, the policy had people on edge.

The policy, not the global, some times lethal, pandemic.

The policy made people not want you near them.

Re:How Many Microbes Does It Take to Make You Sick? by costigan on Monday October 02, 2023 @03:19AM (#37734916)
I was in the south bay, and walked and exercised outside frequently after about the first month. Santa Clara County had a similar policy concerning separation distance outside, and I never had an unpleasant experience. I'm sorry you did, and I won't defend rude or overly fearful behavior. However, I draw a distinction between unintended consequences and weaponization. I've seen no evidence the officials who instituted the policy weaponized anything or directed it toward any specific group or groups, and you have presented none.

My belief is that they were collectively responding to an uncertain, rapidly changing situation, were incentivized to be very conservative given the early experience in Italy, didn't adjust their approach sufficiently when new information revised the case fatality rate downward, and did a poor job overall of balancing the broad spectrum of risks and costs. I don't think any of these mistakes were intentional. And none of us, including those who criticize these policies in hindsight, really know what would have happened had the policies been more lax, especially early on.

Re:How Many Microbes Does It Take to Make You Sick? by AnthonBerg on Sunday October 01, 2023 @06:51PM (#37731787)
That’s bad policy, and obviously harmful.

There we are in perfect agreement.

That policy is also obviously at odds with scientific knowledge.

Policies like that harm high-risks groups immensely too.

Over here, the bad policies were strict social restrictions. Baseless and arbitrary restrictions of the number of people allowed to be at funerals and strict and severe limits to hospital visits. None of these were necessary from the perspective of the reality of aerosolized transmission and how easy it is to strip the pathogen out of the air we breathe.

It’s so absurd that it took a long time to find an analogy. It’s like repairing the flat tire on your bike with a patch of sod. It doesn’t really work, it’s messy, and people will think you’re crazy.

Re:How Many Microbes Does It Take to Make You Sick? by kadoban on Monday October 02, 2023 @12:00AM (#37733834)
> The issue with masks is one side started treating them like a talisman that makes infection impossible, which provoked the other side to say they do nothing.

This is an oddly biased framing.

Re:How Many Microbes Does It Take to Make You Sick? by User23 on Sunday October 01, 2023 @01:48PM (#37728462)
RCTs show surgical and cloth masks to be ineffective or nearly so for reducing the spread of respiratory viruses. Obviously the kinds of masks used in BSL labs do work to prevent spread.

However there are statistics that areas with more masking had less severe illness. However that’s uncontrolled and some other factors or factors might account for both increased masking and reduced spread. That’s probably the case otherwise the RCTs would show efficacy.

All of the subsequent work is just computer models and doesn’t actually tell us anything empirical. Obviously it’s easier to create a model that produces the desired result than it is an RCT.

Re:How Many Microbes Does It Take to Make You Sick? by meowkit on Sunday October 01, 2023 @02:27PM (#37728889)
Established science is an oxymoron.

Science is an on going process, always open to being overturned.

To the point of masks - I agree with your statement here, but a regular mask (filtered masks should help to some extent) will not protect you from an infected person. An infected person with a mask will reduce the chance of spreading their viral load.

This detail is where I feel people are talking past eachother. Most of covid denial to me seems to be about a psychological reactance to being told to mask up when they are not sick.

One might argue that the extra chance of reduced vectorization is worth mask mandates, but that simplistic purely “scientific” approach is its own problem. You have to argue people where they are at and convince them, not force the “right” view on them and then get upset they are “in denial” or skeptical.

https://en.m.wikipedia.org/wiki/Reactance_(psychology)

Re:How Many Microbes Does It Take to Make You Sick? by mozman on Sunday October 01, 2023 @02:35PM (#37728988)
There shouldn’t be any requirements for masks. Want to wear one? Great. Should I have to? No.
Re:How Many Microbes Does It Take to Make You Sick? by amanaplanacanal on Sunday October 01, 2023 @03:01PM (#37729298)
Is fairly common that, if you as an individual are doing something that poses a risk to other people, society will step in to attempt to change your behavior. You can argue that it is “wrong” for society to do that, of course.
Re:How Many Microbes Does It Take to Make You Sick? by maxerickson on Sunday October 01, 2023 @03:15PM (#37729473)
So people shouldn't have freedom of association or control over their own property?

Or do you just mean universal requirements imposed by society at large when you say 'any'?

Re:How Many Microbes Does It Take to Make You Sick? by the_gastropod on Monday October 02, 2023 @11:38AM (#37739518)
It puzzles me that nearly 4 years after the start of the pandemic, this naive libertarian thought fragment is still so widely used. As the saying goes, “Your right to swing your arms ends just where the other man’s nose begins”.
Re:How Many Microbes Does It Take to Make You Sick? by explaininjs on Sunday October 01, 2023 @03:45PM (#37729826)
The simple fact of the matter is that having covid every now and then^ is far superior to wearing a mask always.

^ and the more you have it the less severe it is, until it asymptotically reaches a complete non-issue. As with the common cold.

Re:How Many Microbes Does It Take to Make You Sick? by explaininjs on Monday October 02, 2023 @01:50AM (#37734432)
The downvoters might explain their distaste. But I cant expect them to do more than echo what the government told them.
Re:How Many Microbes Does It Take to Make You Sick? by verve_rat on Monday October 02, 2023 @02:50AM (#37734751)
Yeah, there is a weird grouping of rabid anti-maskers here. Seems odd given the nominal audience of this site.

I just don't get the rejection of basic facts.

Re:How Many Microbes Does It Take to Make You Sick? by JeremyNT on Friday October 06, 2023 @12:57PM (#37793205)
The audience of the site is very entrepreneurial and as such is libertarian leaning by and large.

Which is to say you shouldn't be terribly surprised that there is a general strain of "don't tread on me" in the discourse. Simply being told what to do is enough to elicit a strong negative response.

Re:How Many Microbes Does It Take to Make You Sick? by refurb on Monday October 02, 2023 @07:16AM (#37736705)
No not really.

Infection is binary or not. You either get exposed to enough to actually result in replication inside your body or you don't. If you get exposed to a small amount and your immune system immediately eliminates it, that's not an infection.

The amount of exposure needed to actually cause an infection is different from person to person depending on their immediate immune response.

But it's not like reducing exposure by 50% reduces disease severity by 50%. Biology doesn't work that way.