I had similar problems maybe 15 years ago, so I don't remember exactly how I solved it. In my case it was a NIC driver that filled up some queue when I downloaded "Linux ISOs" too fast over bittorrent.

There are tools available to find the source of the problems, I think I used event tracing as a starting point.

https://learn.microsoft.com/en-us/windows-hardware/drivers/d...

Unplug and try a different mouse. Unplug and disconnect any other peripherals except the mouse and try that. Try a new user on windows (user space apps) Try a fresh install (system stuff) If you have spinning rust try another hard drive (an app doing stupid blocking exclusive stuff with writing or reading can pause input stuff).

Did you do any overclocking (especially RAM)? I've seen issues like this with either slightly unstable OC, or bad drivers.

I'd also suggest running https://www.resplendence.com/latencymon to see if it's a specific driver causing the stalls, or if it's random.

I noticed it after I upgraded to a 3900X. Not sure if it's an AMD thing, a USB hub thing, or a many-core thing. But it had never happened before. (Microsoft Pro Intellimouse)

It's probably an AMD thing. I had the same with a 5800x until I switched to a PCIe/usb card instead of the onboard ports.

You can use UI4ETW[0] to capture an event trace when the mouse freezes. You may need to install the Windows SDK or Visual Studio to interpret the results, though.

[0] https://github.com/google/UIforETW