Maybe not physically, but logically you can, via an external GPU.
Re:Intel is quitting on NUC computers
by etempleton on Tuesday July 11, 2023 @11:09PM
(#36690038)
There are some pretty interesting custom builders on YouTube such as Optimum Tech that do some fascinating custom loop compact builds and then under volt the GPU. Here is a recent one with a 4090: https://youtu.be/X0ukdo7Xx7U
Re:Intel is quitting on NUC computers
by PeterStuer on Wednesday July 12, 2023 @02:35AM
(#36691105)
Unless you are also gaming, the AI machine does not need to be your desktop. But can sit comfortably in your basement, chugging along 24/7 with no compromise adequat cooling.
The new high end application for PCs is running AIs locally.
No way you can fit a 4090 in a NUC, the GPU itself is larger than a NUC, heat dissipation requirements cannot be 'optimized' away.