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A comment on Modern Hunter-Gatherers Have Thriving Gut Microbiome, Compared with Californians.

Re:Modern Hunter-Gatherers Have Thriving Gut Microbiome, Com... by CrHn3 on Monday June 26, 2023 @05:31PM (#36486154)
This article conflates diversity with gut health. It has not been proven that more diversity is necessarily better[1]. In fact, in infants a less diverse b. infantis dominant environment is probably advantageous[2].

If you're having a baby, the best thing you can do is to supplement b. infantis, especially the robust strain from Evolve Biosystems[3]. The Hadza have more b. infantis[4] which kicks off a set of immune host interactions that have positive effects on inflammation during the critical period after birth[5].

"After around 3 years, the gut microbiota stabilises retaining relative proportions of taxa with adaptations to composition harder to impose,"[6] so I doubt it's diet as much as it is vertical transmission of the right kinds of bacteria that set the infants up for a lifetime of healthy immune response.

1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5103657/

2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177445/

3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352178/

4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9894631/

5. https://www.sciencedirect.com/science/article/pii/S009286742...

6. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6950569/

[ Parent | on HN ]
Re:Modern Hunter-Gatherers Have Thriving Gut Microbiome, Com... by dmbche on Monday June 26, 2023 @06:59PM (#36486993)
I'm surprised you're downvoted, you liked 6 papers and are just stating that the link is tenuous, I think that's fair.
[ Parent | on HN ]
Re:Modern Hunter-Gatherers Have Thriving Gut Microbiome, Com... by Fricken on Tuesday June 27, 2023 @10:54AM (#36493773)
The parent opened their comment with a false claim. At no point did the article conflate gut diversity with gut health.
[ Parent | on HN ]
Re:Modern Hunter-Gatherers Have Thriving Gut Microbiome, Com... by FollowingTheDao on Tuesday June 27, 2023 @09:05AM (#36492160)
Also, never ever ever do they mention anything about human genetics. There are people who carry more hunter-gatherer traits than others. So who is this diet really for?

Genetics matter. I am a FUT2 non-secretor and this effects my gut health tremendously. I had IBD-D for years before I found this out. Before then if I took any pre or pro-biotics it was a nightmare, but that was supposed to be the healthy thing to do.

So sorry, but I do not listen to any nutritional research anymore that over generalizes a genetically diverse population.

https://www.nature.com/articles/ismej201464

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9866411/

[ Parent | on HN ]