Well, brain and face diseases and cancers would still be a problem. "rejuvenate youth" is a magic phrase in there that promises a lot but doesn't actually mean much.

> "rejuvenate youth" is a magic phrase in there that promises a lot but doesn't actually mean much.

I disagree; though the phrase and its synonyms hides a lot of complexity — and I have to temper my optimism about research with the knowledge of millennia of snake oil — we'd recognise it if we saw it. (Unlike, say, "is this AI/animal conscious?", where we can't agree what the question means).

Would we? What all comes with "rejuvenate youth"? We have technology right now that makes one LOOK younger. Is it more than that? Where does it stop? Do our brains have to reverse their development so that the bits that don't fully congeal into our late 20's/early 30's are removed? Do we need to become impulsive, awkward, hormonal weirdos again? What's youth? 35? 25? 15? Does youth requiring scraping out all the plaque out of our arteries? Do we remove our scars? Do we get acne again?

A lot of what makes us us with all the wisdom of our age is also the bits that lead to the eventual breakdown and decay of our body. I think we'd need to lose ourselves to get our "youth" back. We're hoping for some magic where we keep all the good with none of the bad.

We've pretty much already done this with rats. The pop-sci summaries of the research I've seen (with all the caveats implied) say this improves cognition and memory, as well as general physical health and (because rats) fur colouration and quality.

Sadly, the usual problem is that rats aren't really very close to humans, merely closer than the other stuff we research with.

I assume none of that involves creating a braindead clone of the mouse?

Not that I heard, though it doesn't matter either way with regard to the specific issue I was critiquing.

Yeah, fair enough. The goal isn't necessarily magic. But I feel like the way to get there, at the moment, mostly is, especially with something like comparing a mouses lifespan against ours.

Sounds awful. Like my life of course and would be bummed if I fell over and died due to organ loss but OTOH I don't share the fondness for immortality or crippling fear of death that seems to affect many technologists. It seems just as natural that things should have ends as beginnings.

I don't fear death, but what I don't like are constant health problems when you get older. My grandma complained about her health problems constantly - it was so annoying.

There is also a strong influence of mindset here: there are people who are psychologically able to handle far more painful situation and still enjoy whatever satisfaction reachable to them, when other will lament all day along how sad they feel when they have best health and great social situation but can’t afford whatever luxury thing that might be above their current wallet.

To be clear, this is not to blame your grandparent. We all deal with situation with behavior that life forged into us. But if your opinion is that free will exists, then you should probably agree that there are ways to improve ourself.

Old people have measurably more health problems though, it does look uncomfortable. If there is an option to avoid that, it would be better.

Well, start take care of oneself, regular but not exaggerated physical exercices, good nutritional habits, sleeping enough each day and having balanced social interactions: these are all well known and documented.

Not ways to live to 200.

No cloning can produce what your body accumulates while interacting with enviroment. Lookup epygenetics.

Surely that is a good thing in this case?