Can you name some?
Back in 1999 my relatives were mostly running Internet Explorer on computers with 640x480 screens over dialup. It was fashionable then for companies like Yahoo! and Hotmail and Amazon to add toolbars to your web browser and I'd go visit my uncle and find that more than half of the vertical space was taken up by various toolbars they'd downloaded so they really had about 300 pixels to view the web through.
None of them seemed to thing there was a problem there.
Similarly today if you install too many plugins into a GUI application and it gets "pluginitis" and gets slow and unreliable. I am all for extensions that really speed things up by eliminating junk but if you're not part of the solution in this way you are part of the problem.
Unfortunately with IDEs for instance, many people have never had the experience of using an IDE that "just works", they expect it to be f-ed up all the time so when they load another 15 plugins into Eclipse and it is crashing and hanging up all the time they figure "that's life" and don't even realize that somebody else has a stable IDE because they use a stable set of plugins and don't have pluginitis.
Reliability and speed are features too and they are global properties of the system. I'd say non-GUI programs accept extensions well but GUI programs have a rendering thread that can be blocked, an internal change notification system that can be corrupted or used incorrectly, etc.
Lots of new features were impossible with the old extension model, which was barely an extension model so much as complete access to the browser internals.