Re:How Peptide Injections Became the Answer to Everything
by GeoRandel on Saturday March 04, 2023 @10:33AM
(#35021518)
Would BPC-157 be something that could be packaged in a liposome? Everything I've read about liposomal supplements has pointed to it having superior absorption, distribution and bioavailability when compared to injection
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Re:How Peptide Injections Became the Answer to Everything
by A_D_E_P_T on Saturday March 04, 2023 @03:35PM
(#35024262)
Yeah, you can incorporate BPC-157 and other small peptides into liposomes.
Liposomal delivery might even work for far larger peptides and proteins. For e.g., there has been quite a lot of research into liposomal insulin: https://pubmed.ncbi.nlm.nih.gov/2226109 and others.
The thing about BPC-157 in particular is that it has, in principle, pretty good oral bioavailability, and it's not clear that it would benefit from liposomal delivery. You'd probably want to run a comparative analysis -- liposomal suspension vs. plain aqueous solution -- which would be expensive no matter how you go about it.