Well, it's not so clear, even though I reject wokeness. For example, what's the gender of eunuchs from the middle ages? They hardly pass as males, but they are even further from females.

Obviously male. Having one's testicles removed doesn't change you from a boy or man to something else in that category.

That's a mutation of the reproductive system of the class Gender with male as the value, also known as a sex. Still a male, with their mutation event modifying the state of their reproductive system into damaged, one that is different from the original state. That does not change the class but simply the value of a property within that class.