Lisp was Python in the first AI wave, and having it failing to meet expectations burned many bridges.

Commercial software + hardware required to comfortably run Lisp Machines was more expensive than UNIX workstations.

Having paid for UNIX workstations, most shops would just use C and C++ instead of paying for commercial Lisp packages on top, plus scripting languages like Tcl and Perl brought a bit of Lisp like experience into UNIX.

Eventually most of the stuff that made Lisp awesome ended up in Smalltalk, Java. .NET, Dylan, Julia, Python however there is still plenty missing from the whole experience.

Sorry, couldn't parse your comment. What do you mean to ask when you ask what significantly else? Examples of companies that use Lisp? The link in the comment you are replying to does not answer that?

Maxima, the CAS system

Are you perhaps implying programming languages are chosen on technical merits?

The Interleaf document creation software was written in Lisp:

https://en.wikipedia.org/wiki/Interleaf

It lives on today as Broadvision QuickSilver, which still runs on Lisp:

https://broadvision.com/broadvision/quicksilver/quicksilver-...

The whole Clojure ecosystem is another worth considering, including systems like Datomic, and Datomic Cloud (commercial product and SaaS product respectively).