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Re:Butterfly wing patterns emerge from ancient ‘junk’ DNA by lmpdev on Saturday October 22, 2022 @02:13AM (#33295985)
I feel like at this point I need a browser plugin which changes the phrase "junk DNA" to literally any other phrase

One of the worst names I've come across for a concept

Re:Butterfly wing patterns emerge from ancient ‘junk’ DNA by epistasis on Saturday October 22, 2022 @02:17AM (#33295994)
True enlightenment is when you realize that junk DNA is actually a great term, because evolution is great at building things out of junk and repurposing them.

The "junk" areas of repetitive DNA were actually identified as cauldrons of evolution in the early days of research, so we have known since the beginning that the junk was actually crucial.

Barbara McClintock's Nobel for this was awarded way back in 1983

https://en.wikipedia.org/wiki/Barbara_McClintock

Re:Butterfly wing patterns emerge from ancient ‘junk’ DNA by jakobnissen on Saturday October 22, 2022 @03:26AM (#33296262)
This is a pet peeve of mine - the common misconceptions that "junk DNA" is just DNA with an unknown function.

By far most junk DNA really is junk. We know this because we know its nonfunctional origin (transposons, pseudogenes and similar), because we can do studies of conservation between species, and because there is a huge range of junk DNA content in otherwise similar species.

The misconception come from media bias: You'll never hear a story about "junk DNA really is junk, researchers find"

Re:Butterfly wing patterns emerge from ancient ‘junk’ DNA by vbezhenar on Saturday October 22, 2022 @03:53AM (#33296355)
Does it mean that mutations in the junk DNA are evenly distributed among the population because supposedly they don’t affect anything?
Re:Butterfly wing patterns emerge from ancient ‘junk’ DNA by Fubwubs on Saturday October 22, 2022 @11:36AM (#33299156)
Transposons and pseudogenes may be nonfunctional for an individual organism, but aren't they useful for evolution to create new genes? Wikipedia suggests some usefulness:

"While some TEs confer benefits on their hosts, most are regarded as selfish DNA parasites" (https://en.wikipedia.org/wiki/Transposable_element#Evolution)

"Pseudogene sequences may be transcribed into RNA at low levels, due to promoter elements inherited from the ancestral gene or arising by new mutations. Although most of these transcripts will have no more functional significance than chance transcripts from other parts of the genome, some have given rise to beneficial regulatory RNAs and new proteins." (https://en.wikipedia.org/wiki/Pseudogene)

I would define truly junk DNA as any DNA that if removed would be beneficial or not harmful to the majority of organisms in a species, and be beneficial or not harmful to the ability of a species to adapt and evolve its genome.

Re:Butterfly wing patterns emerge from ancient ‘junk’ DNA by xg15 on Saturday October 22, 2022 @05:28PM (#33302395)
> Transposons and pseudogenes may be nonfunctional for an individual organism, but aren't they useful for evolution to create new genes?

Ok, but by that definition, nothing is really junk: Even our own junkyards are still home to all sorts of animals and microorganisms which feed on the junk.

Not even starting with the recycling/upcycling movement.

Doesn't change the fact that it's junk in the sense of its original purpose and immediate utility to us.

In the same way, if junk DNA really has no effect on the body it's currently part of (like freed but uncleared memory in RAM), then I think the name is appropriate.

What I'm really missing in popular reporting about genetics though is more focus on the "regulatory elements". The understanding of DNA as given by pop-science articles is mostly that DNA is either instructions for building proteins or "junk", nothing else. This completely leaves out the question how the cell decides when/if a particular protein should be built - which is of course integral for understanding how a number of protein building instructions can result in a complex organism.

It's like describing a programming language as consisting only of instructions and comments but completely leaving out branches and loops.

(even though gene regulation does not happen through branches and loops)

Re:Butterfly wing patterns emerge from ancient ‘junk’ DNA by pwdisswordfish9 on Saturday October 22, 2022 @04:17AM (#33296462)
How about "cloud computing"?
Re:Butterfly wing patterns emerge from ancient ‘junk’ DNA by thanatos519 on Saturday October 22, 2022 @05:13AM (#33296698)
How about "legacy DNA" or "retired DNA" or just "leftovers"?
Re:Butterfly wing patterns emerge from ancient ‘junk’ DNA by Gatsky on Saturday October 22, 2022 @06:35AM (#33297083)
Of course, nobody who does biological sciences actually believes it is junk.
Re:Butterfly wing patterns emerge from ancient ‘junk’ DNA by lrhegeba on Saturday October 22, 2022 @10:28AM (#33298578)
"deprecated DNA" seems a good fit ;-)