Re:Dextromethorphan-Bupropion in Major Depressive Disorder: ...
by mpalczewski on Wednesday September 28, 2022 @06:32PM
(#33014089)
TLDR:
Have some cough syrup with your Bupropion (anti-depressant) for increased efficacy.
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Re:Dextromethorphan-Bupropion in Major Depressive Disorder: ...
by genewitch on Wednesday September 28, 2022 @06:35PM
(#33014110)
Guaifenesin, another ingredient in most cough syrups, is also used in muscle relaxants.
Who knew that "more tussin" would be the answer?
Re:Dextromethorphan-Bupropion in Major Depressive Disorder: ...
by astrange on Wednesday September 28, 2022 @09:18PM
(#33015259)
The worst thing about guaifenesin is there's also an ADHD medicine called "guanfacine" and if you take that everyone, including doctors, thinks you meant the other one.
You could say Tenex instead but it sounds like a telecom company.
Re:Dextromethorphan-Bupropion in Major Depressive Disorder: ...
by floatinglotus on Wednesday September 28, 2022 @08:06PM
(#33014764)
Mo tussin! Mo tussin!
Re:Dextromethorphan-Bupropion in Major Depressive Disorder: ...
by orangepurple on Wednesday September 28, 2022 @08:16PM
(#33014838)
Initially I thought this was lean or sizzurp but that is codeine and promethazine cough syrup so its not the same.
Re:Dextromethorphan-Bupropion in Major Depressive Disorder: ...
by schwartzworld on Wednesday September 28, 2022 @06:36PM
(#33014116)
Guaifenesin also makes you puke if you have too much.
Re:Dextromethorphan-Bupropion in Major Depressive Disorder: ...
by sallystarace on Wednesday September 28, 2022 @06:41PM
(#33014158)
Dextromethorphan tolerance builds so rapidly. I have found the withdrawal to be hell after taking it legitimately for a cold longer than I realized. I have tried SSRIs and found that they also have a synergetic effect with Bupropion (good medicine). SSRIs also make me drowsy, but at least they can be sustainably taken daily for months.
Re:Dextromethorphan-Bupropion in Major Depressive Disorder: ...
by mmastrac on Wednesday September 28, 2022 @07:47PM
(#33014640)
I had good luck with a prescribed combo of modafinil + buproprion. No drowsiness, much higher motivation.
Re:Dextromethorphan-Bupropion in Major Depressive Disorder: ...
by hungrigekatze on Wednesday September 28, 2022 @11:01PM
(#33015841)
Does that lower the seizure threshold at all? (I've had docs get on my case about bupropion + mild other medication that can in theory impact the seizure threshold) But I'd be interested - potentially - in trying this combo as things are pretty cobwebby in the brain department lately.
Re:Dextromethorphan-Bupropion in Major Depressive Disorder: ...
by epicureanideal on Wednesday September 28, 2022 @07:53PM
(#33014680)
Modafinil alone didn’t have that effect?
Re:Dextromethorphan-Bupropion in Major Depressive Disorder: ...
by mmastrac on Wednesday September 28, 2022 @08:27PM
(#33014910)
It helped, but the combo beat both depression and lack of motivation much more effectively.
Re:Dextromethorphan-Bupropion in Major Depressive Disorder: ...
by gremlinsinc on Thursday September 29, 2022 @04:56AM
(#33017996)
Sounds like me, except Vyvanse instead of Modafinol. Bupropion was the magic key. I thought my Vyvanse just wasn't working anymore.
Turns out I was just super depressed. Since switching meds I've lost a lot of weight because I don't have food cravings as much.
The way I think of it... Vyvanse keeps me focused when I get to work, but without Bupropion just getting out bed sometimes seems daunting. One gets me to start my day, the other keeps me focused when I do.
Re:Dextromethorphan-Bupropion in Major Depressive Disorder: ...
by floatinglotus on Wednesday September 28, 2022 @08:07PM
(#33014770)
What dosage of modafinil?