Microdosing with psilocybin mushrooms: a double-blind placebo-controlled study

Re:Microdosing with psilocybin mushrooms: a double-blind pla... by hackernewds on Saturday August 06, 2022 @01:31PM (#32369960)

the importance of "set and setting" is almost universally known and easily verifiable. I've had terrible trips when stressed out and beautiful revelational ones when in the right frame of mind. shrooms are not as benign as alcohol. you're usually even less in control of your mental state, which can be both amazing and scary

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Re:Microdosing with psilocybin mushrooms: a double-blind pla... by YeGoblynQueenne on Saturday August 06, 2022 @01:57PM (#32370192)

I don't dispute the "set and setting" idea. I am asking why that makes a difference in the therapeutic or otherwise beneficial use of psilocybin and why it doesn't make any difference with other drugs like aspirin.

To clarify, as far as I understand, "set and setting" matters when taking psilocybin to get high, but microdosing is taking psilocybin (or other similar drugs) to very deliberatly not get high.

So what does "set and setting" have to do with microdosing, and why doesn't it matter with aspirin, which also doesn't get you high?

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Re:Microdosing with psilocybin mushrooms: a double-blind pla... by xolox on Sunday August 07, 2022 @05:49AM (#32375198)

In the context of taking psychoactive mushrooms to get a proper trip, there are the concepts of a good trip, a bad trip, and steering your trip towards the former and away from the latter, based on your thought patterns and emotions (so actively pursuing the intent to have a good trip in your mind).

Now I've never microdosed mushrooms, but it's not hard for me to imagine that this same concept applies, of actively pursuing a good experience, which can steer that experience in a good direction. It will just be at a much smaller scale.

For myself I think of this phenomenon as a kind of self-fulfilling prophecy (not meant as a judgement about others) which helps me to keep in mind that I'm the one in control (assuming doses are not excessively high, I think others in this thread call those "heroic doses").

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