You wouldn't be flying this over bodies of water which could have rogue waves. Those are generally open sea scenarios, and this is really only practical for hops between relatively close bodies of land, over water. There are a lot of such places around the world, even some where the water is technically connected to an ocean.

In terms of risk of life, it's probably less risk than taking a 180 mile bus ride... even if it were crossing water which could conceivably have a rogue wave appear.

Yeah Miami to Nassau seems like a decent candidate.