Re:The gut metabolite indole-3 propionate promotes nerve reg...
by feet on Wednesday June 29, 2022 @11:41AM
(#31921740)
I suspect you may be right. Many supplements that have been tried just get broken down in digestion and don't actually increase target levels in the target tissues, rather we need to find ways of increasing the intake of precursor or figuring out which microbiota are involved in the metabolism and giving them a helping hand or just adding them altogether
Re:The gut metabolite indole-3 propionate promotes nerve reg...
by fredophile on Wednesday June 29, 2022 @11:45AM
(#31921780)
I don't have a citation handy but I know eating fermented foods and increased fiber have both been linked to increased gut bacteria diversity. Thus seems in line with what the GP poster found for practical advice.
Re:The gut metabolite indole-3 propionate promotes nerve reg...
by Melatonic on Wednesday June 29, 2022 @12:38PM
(#31922521)
Its all about PREbiotics which are the food source for probiotics or your gut bacteria. Which encompasses some fiber and also sort of is its own thing. Long chain inulin and resistant starch are both some good ones
This leads me to believe that trying to increase indole-3-proprionate specifically may be a fruitless journey (pun not intended), and one would be better off by optimizing for a hospitable environment for beneficial microbes in general, for example by cutting out carbs but increasing intake of flavonoids.