Good luck with the visa and cultural barrier if you like families.
I remember cruising through the streets of Tokyo in the middle of the night, still worried that I might get jumped by a meth hear even though it was extremely unlikely. It's a pre-conception that is hard to let go of.
The language barrier is the biggest issue. Assuming you live in a large city (and really, you should), the town halls have translators. You may need to wait for them to be available, and the translations may not be amazing, but they'll help you solve any tasks you need to do.
The next biggest issues are getting a phone number (you need a residence card first), getting a bank account (you need a residence card and a phone number), and getting a credit card (you need a residence card, a phone number, and will need to deal with them sending your card with your katakana name on the envelope). If you have a job, they'll help you do all of these things.
Getting housing isn't really a problem. At this point there's lots of gaikokujin housing (short-term rentals, month-to-month leases, sharedhouses, etc). It's possible to find it online with no Japanese language skills. Again, if you have a job, they'll help you find housing.
If you're coming in as a student, your school will also help you with all of these things.
Pewdiepie makes money off of making content. Saying "hey, this isn't very hard" isn't entertaining. Don't use him as a real-life example.