Ideal indoor air quality is equal to outdoor air quality. This can only be achieved through air exchange. The ventilation process may be 100% efficient but the consequences of pumping outside air in and inside air out are the same. The air must be heated and costs some unit of energy to accomplish.
Ideal indoor air quality is (can be) better than outdoor air quality. This is because when the outside air is brought in it passes through filters to get rid of things like dust and pollen.
> The air must be heated and costs some unit of energy to accomplish.
Unless you use passive solar thermal, i.e., let the sun heat the home:
* https://www.energy.gov/energysaver/passive-solar-home-design
Look up HRV/ERVs.
You'll have better air quality by building a tight envelope and using mechanical ventilation because all the air from the outside will flow through filters. It then gets tempered by the exhausted stale air before being circulated.
A leaky house and ventilation through windows was fine in the 1920s, but we've better ways now.
(And operable windows won't go away: they're mandated for fire egress. So you can crack one open if you wish.)