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Re:Single psilocybin dose may make lasting personality change by throwaway7-2521 on Friday September 30, 2011 @04:36AM (#3056216)
Somewhat odd to have used OJ as the mixer; vitamin-C is often considered to accelerate the breakdown of psychoactive substances (especially those like MDMA and LSD), so would normally be avoided until you feel you're 'done' and want things to end.
Re:Single psilocybin dose may make lasting personality change by sophacles on Friday September 30, 2011 @09:16AM (#3056824)
I've always been told it enhances the experience...

Anyway, it doesn't follow that faster breakdown makes the trip end... could be that the very process of breaking down the active substance produces the effects desired, and the vitamin-C acts as a catalyst to "even out" the experience.

Re:Single psilocybin dose may make lasting personality change by shabble on Friday September 30, 2011 @12:03PM (#3057481)
You might be confusing the OJ/vitamin C with the properties of grapefruit juice, which is well-established to alter the properties of various liver enzymes, particularly those which typically metabolise psychedelic / hallucinogenic drugs. Wikipedia has a brief blurb about it: https://secure.wikimedia.org/wikipedia/en/wiki/List_of_drugs...

Actually, it does mention orange juice as containing flavonoids which may have some (albeit lesser) effect on drug metabolism.

Re:Single psilocybin dose may make lasting personality change by sophacles on Friday September 30, 2011 @01:24PM (#3057799)
Fair enough, but doesn't Grapefruit Juice contain a high vitamin C content also?
Re:Single psilocybin dose may make lasting personality change by shabble on Friday September 30, 2011 @05:24PM (#3058625)
Yeah. Actually, it looks like there is mention in the literature (Simon Wills Drugs of abuse, 2nd Ed, 2005)[1] of vitamin C in fruit juice, or Ammonium Chloride to acidify urine to promote sequestration and removal of amphetamine metabolites.

I'm not sure if/how that translates to other drugs like Psilocybin, but it does raise some interesting questions. Do you by any chance have a source regarding the original "enhances the experience" statement? (for my own curiosity really - I'm not saying that you're wrong or misinformed)

[1] http://books.google.com/books?id=_m7gPani5D4C&lpg=PA124&...

Re:Single psilocybin dose may make lasting personality change by sophacles on Tuesday October 04, 2011 @02:44PM (#3072235)
No real source, but googling "vitamin c mushrooms ehance" brings up lots of forum posts etc. In my case, this knowledge is just the sort of folk-wisdom picked up from a misspent youth :). I have heard lots of stuff to explain it, but all of that falls squarely in the "probably pseudoscience" and [citation needed] categories.

HTH

Re:Single psilocybin dose may make lasting personality change by majorlazer on Friday September 30, 2011 @08:38PM (#3059034)
Vitamin-C does virtually nothing for the trip. It's all placebo.

Now, if you grind the mushrooms up and let them site in lemon juice for 30+ minutes. That will definitely accelerate the time you reach the peak of the trip. The acids in the lemon juice break down the mushrooms so the stomach can digest them more quickly.

Re:Single psilocybin dose may make lasting personality change by wellsaid on Friday September 30, 2011 @03:37PM (#3058293)
I agree, orange juice is a must-have on any trip.