Do you mean "leave your house... to work somewhere else"? If so, that's sort of an option. But at that point, I might as well be working with my coworkers.

If you mean "leave your house... outside work hours", this is also becoming more and more possible, yet most of my waking hours are part of my workday.

I've been working remote for over a decade now - the first eight of which were under non-pandemic conditions. Working from a coffee shop, from a park, from a plane or train are all eminently possible, and variation is the key to things being enjoyable.

Unfortunately the pandemic has sent middle managers mad for video calls and status updates, which has made things generally less productive.

This. Before the pandemic I'd go work from somewhere nice once or twice a week. That made home not that boring. Not possible anymore with the pandemic, although things are starting to feel normal again and last week I worked from a coffeeshop in front of a nice lake which was wonderful.

Do "work hours" apply? If so, yes, outside of them.

Leave your house to exercise, to do some task, to just see people going around. Do not stay all your time outside of work alone, go somewhere where there are people, and meet them. It doesn't need to be every day, but often enough.

Work from a co-working space. You get the social aspects with more freedom (to move spaces, to be friendly or frosty with a co-tenant without risking employment, etc). I co-own a co-working space and we have part-timers and remote workers in the mix.

Getting out is important. Go outside. Play in the rain. Do yard work. Go for walks. Get sun.

Either or both.