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Re:Lab-grown meat may never be cost-competitive enough to di... by fabian2k on Wednesday September 22, 2021 @05:34PM (#28622158)
If you use current technology for growing cells I can easily believe that it will never be competitive. Even with economies of scale that is rather sensitive work that is very easily spoiled. Unless you figure out how to ensure clean-room conditions for low cost this part alone might make this too expensive.

But I don't see how there could be any kind of insurmountable problem here. Animals "solve" this problem for us right now, so there is a way. I just think that the solution has to be quite different than how we grow cell cultures in the lab right now.

Short term I'd be really skeptical on the prospects of replacing meat in this way. But long term is an entirely different question.

Re:Lab-grown meat may never be cost-competitive enough to di... by lazerpants on Wednesday September 22, 2021 @05:43PM (#28622270)
It's like looking at the Wright Flyer and saying that it is neat proof of concept, but that affordable transatlantic flight will simply never be possible. Prescient at that point in history, but myopic over a long enough time frame.
Re:Lab-grown meat may never be cost-competitive enough to di... by ChrisMarshallNY on Wednesday September 22, 2021 @05:59PM (#28622506)
I'm surprised it was downvoted. It was a good point. Those of us in the computer industry can well remember when "640K should be enough for anyone."

We literally cannot imagine what the future will bring. I'm still waiting on my flying atomicar.

I think it will end up being necessary to make food this way, and that we'll figure out how to do it (Soylent Green, anyone?).

Re:Lab-grown meat may never be cost-competitive enough to di... by 2muchcoffeeman on Wednesday September 22, 2021 @10:11PM (#28624517)
These sorts of things look like inspirational posters and suffer from survivorship bias. Many more ideas failed than succeeded.

We also seem to think that no one learned from all that experience. We can see the things that made something once thought impossible work at scale. We all know these stories. So we’re more primed to be wary of just being negative.

I’m all for spending money on this, but it could turn out certain breakthroughs are needed and we don’t know when or if they will come.

Re:Lab-grown meat may never be cost-competitive enough to di... by White_Wolf on Wednesday September 22, 2021 @06:57PM (#28623108)
I do have times when I look at my phone and think about the first "computer" I touched. I'm still amazed sometimes of how tech changed since I was 6-7 years old(talking almost 40 years)

I'm no fan of lab growing anything because or banning people from raising animals or having food plots because those that make the food make the rules. That being said... I wouldn't be suprised to see, in 2-3 decades, something taking off in that regard. All it takes is one stroke of genius and a ton of elbow grease to change it all.

Re:Lab-grown meat may never be cost-competitive enough to di... by randomdata on Thursday September 23, 2021 @09:56AM (#28629197)
> Those of us in the computer industry can well remember when "640K should be enough for anyone."

I can remember the urban legend, but there seems to be no solid evidence that it was ever actually said, let alone believed by anyone. The saying is normally attributed to Bill Gates, but he denies ever saying it, and tells how he was pushing computer makers to include even more RAM.

Re:Lab-grown meat may never be cost-competitive enough to di... by ChrisMarshallNY on Thursday September 23, 2021 @10:09AM (#28629373)
That’s why I didn’t attribute the quote. I’m quite aware that the attribution is probably B.S.

There’s no question that the attitude was prevalent, though; whether or not Gates said anything like it.

“Don’t believe everything you read on the Internet.”

—Abraham Lincoln

Re:Lab-grown meat may never be cost-competitive enough to di... by randomdata on Thursday September 23, 2021 @10:21AM (#28629547)
When 640k was all you could reasonably buy as a consumer, it had to be enough for anyone if you wanted to own a computer at the time. It was never thought of as some fundamental limit that could not be broken or utilized in larger quantities, however.
Re:Lab-grown meat may never be cost-competitive enough to di... by Jensson on Wednesday September 22, 2021 @08:17PM (#28623771)
Most things people said wouldn't happen didn't happen though. Some remarkable things happened, yes, but you can't count on remarkable breakthroughs happening in any specific area.

People looked at past results and thought we would live forever by now, but we still die and there is no end in sight of that.

People looked at past energy use and saw the future of fusion solving all human energy needs, but energy use has been flat for the past 50 years as no new efficient enough energy sources was found.

People looked at the innovations of transportation and assumed we would all have flying cars today, yet we still drive cars on the ground just like 70 years ago. They are a bit safer and more efficient today, but they are still just cars.

Re:Lab-grown meat may never be cost-competitive enough to di... by beambot on Wednesday September 22, 2021 @08:47PM (#28623972)
Fwiw, net-positive nuclear fusion now legitimately looks to be less than 5 years out. See Commonwealth Fusion. Here's a technical deep dive:

https://youtu.be/rY6U4wB-oYM

Re:Lab-grown meat may never be cost-competitive enough to di... by Jensson on Wednesday September 22, 2021 @09:02PM (#28624063)
Those slides was 2.5 years ago, there ought to have been some very interesting development since then if it is just 5 years away, right? Can't you link something more recent?
Re:Lab-grown meat may never be cost-competitive enough to di... by beambot on Wednesday September 22, 2021 @09:10PM (#28624112)
Most recent advances: https://news.mit.edu/2021/MIT-CFS-major-advance-toward-fusio...

I just figured the physics symposium lecture would be more interesting given the deep-dive details and allusions to why ITER "failed" to achieve the desired breakthroughs.

Re:Lab-grown meat may never be cost-competitive enough to di... by pas on Thursday September 23, 2021 @03:07AM (#28626066)
(Just to elaborate on ITER. It's the classic too big to fail project, not to mention it has basically one feature: it's so over-engineered that it can't fail. It's almost the equivalent of the LHC. Built to "prove" a theory. Of course almost everyone wished some beyond the standard model physics to pop up at the LHC, it didn't as far as I know. Almost nobody wishes for unexpected things to happen at ITER, so it's supre boring. With a really eye-watering price tag. But at the same time it is a big umbrella project to get the necessary components designed, built, and tested for fusion. It's accumulating know-how, training experts, it's literally paving the fucking way. Hence the name. And in that context it's basically free. Companies spend more on filing and litigating dumb parents, and those are obvious too.)
Re:Lab-grown meat may never be cost-competitive enough to di... by Jensson on Wednesday September 22, 2021 @09:18PM (#28624173)
Thanks, that looks cool. Just that a professor with slides is rarely a good sign that something is soon production ready, but them meeting production milestones is a good sign.

Still I wont bother to check the physics, if they are right it is great, but I wont change my life based on them making it. I know the problems with ITER, it will be too expensive to really revolutionize much, but I haven't done physics in a while and wont bother with more now.

Re:Lab-grown meat may never be cost-competitive enough to di... by vladTheInhaler on Wednesday September 22, 2021 @07:34PM (#28623413)
Agreed. Skimming Humbird's analysis, he mentions concentrations of catabolites as a significant limit on cell density, and points out that their removal is usually the job of the kidneys. To me that immediately raised the question of how to design an artificial kidney-like structure that can also live in solution. Similarly, the cleanroom conditions are very difficult to sustain, but what if we could engineer a replacement for the immune system to police the reactors?

Both of those are of course complete science fiction currently, but they're not "thermodynamically impossible" like he seems to suggest. They're 'just' conditioned on a significantly deeper understanding of biochemistry and genetic engineering than we currently have.

Given the current state of the technology and the implications of meat for global warming, I suspect that meat might just become more expensive until it stops being eaten entirely. And when the technology exists to produce it artificially, there won't be a market for it anymore. Speaking as someone who eats meat regularly, it's mostly a matter of conditioning. I don't think I would have independently invented the idea of killing and consuming an animal if other's hadn't taught it to me.

Re:Lab-grown meat may never be cost-competitive enough to di... by Jensson on Wednesday September 22, 2021 @08:00PM (#28623626)
If you solve those issues cost efficiently enough to grow meat cells you basically also solved all human blood and heart diseases. Just run your artificial kidneys to clean the blood etc. It isn't impossible to solve as you say, but solving it would basically revolutionize all of medicine.
Re:Lab-grown meat may never be cost-competitive enough to di... by roca on Thursday September 23, 2021 @07:45AM (#28627851)
"Engineer a replacement for the immune system" sounds insanely hard. Problem statement: "constant incoming stream of incredibly diverse unknown bacterial and viral invaders that you have to recognize and kill before their replication overwhelms your systems, but make sure you don't attack any of your own extremely diverse tissues, oh also those bacteria and viruses are constantly evolving to bypass your defenses". Natural immune systems are incredible biotech and it's a miracle we're not all dead.

> I don't think I would have independently invented the idea of killing and consuming an animal if other's hadn't taught it to me.

If you were really hungry I think you'd figure something out.

Re:Lab-grown meat may never be cost-competitive enough to di... by vladTheInhaler on Thursday September 23, 2021 @10:56AM (#28630068)
I completely agree on your first point. I was going for a bit of understatement, but to be clear, doing any of that is firmly on the other side of many revolutionary breakthroughs in our understanding of biology. But that being said, the standard for success isn't to have an immune system that can protect a complete animal for its entire life. The standard is to put up a nonzero amount of resistance to the reactor getting colonized by opportunistic bacteria (yeast etc), and not attack the one specific cell type that you care about. It's about pushing the requirement for sterility down from 100% to 'only' 99.99%.
Re:Lab-grown meat may never be cost-competitive enough to di... by tablespoon on Thursday September 23, 2021 @12:26PM (#28631381)
> Agreed. Skimming Humbird's analysis, he mentions concentrations of catabolites as a significant limit on cell density, and points out that their removal is usually the job of the kidneys. To me that immediately raised the question of how to design an artificial kidney-like structure that can also live in solution. Similarly, the cleanroom conditions are very difficult to sustain, but what if we could engineer a replacement for the immune system to police the reactors?

But then you're talking about re-engineering complex animal life, which is nowhere close to happening any time soon. Plus once you add those systems back in, you may loose most of the energy savings that make "lab grown meat" look attractive. This comment when into more detail and did some back of the envelope calculations: https://news.ycombinator.com/item?id=28623349.

> Speaking as someone who eats meat regularly, it's mostly a matter of conditioning. I don't think I would have independently invented the idea of killing and consuming an animal if other's hadn't taught it to me.

To be fair, you're a human: you had to learn all your survival skills. You wouldn't have independently invented the idea of eating plants either, let alone picking the ones that would give you a nutritionally complete diet without poisoning you.

Re:Lab-grown meat may never be cost-competitive enough to di... by Jeff_Brown on Wednesday September 22, 2021 @07:11PM (#28623238)
> how to ensure clean-room conditions for low cost

Maybe rather than chlorine or UV or whatever, give the clean rooms immune defenses?

Re:Lab-grown meat may never be cost-competitive enough to di... by beerandt on Wednesday September 22, 2021 @08:08PM (#28623697)
There's UV light in sunshine. Maybe they should grow the protein outside.