Valneva and Pfizer announce Phase 2 study for Lyme disease vaccine candidate

Re:Valneva and Pfizer announce Phase 2 study for Lyme diseas... by EdwardDiego on Thursday August 26, 2021 @08:56AM (#28314322)

Why would it though?

mRNA vaccines just get your body to produce a particular protein you want to induce an immune response to, instead of injecting the protein directly.

Is it really the slow uptake of mRNA techniques that's prevented an HIV vaccine? Or is it HIV's capacity for rapidly mutating into large numbers of disparate strains inside one person, let alone in the entire community?

I mean, look at the delta variant of Covid, the mRNA vaccines reduce the severity of infection, but do not prevent infection or spreading thereof.

mRNA vaccines will enable rapid iteration, which is good. But they're not a wonder drug at all.

[ Parent | on HN ]

Re:Valneva and Pfizer announce Phase 2 study for Lyme diseas... by GrinningFool on Thursday August 26, 2021 @09:11AM (#28314445)

> I mean, look at the delta variant of Covid, the mRNA vaccines reduce the severity of infection, but do not prevent infection or spreading thereof.

I keep seeing that surface here. It is at odds with what I'm reading that says it /is/ effective at preventing infection[1] though not perfectly so. Are we looking at different metrics, or is my own ignorance of the field preventing me from fully understanding what I"m reading?

[1] most recently - https://www.cdc.gov/mmwr/volumes/70/wr/mm7034e5.htm?s_cid=mm...

[ Parent | on HN ]

Re:Valneva and Pfizer announce Phase 2 study for Lyme diseas... by bluGill on Thursday August 26, 2021 @09:47AM (#28314872)

The anti-vaxxine crowd has never had any problem with cherry picking the statistics that they can twist to show their view. I've been watching them do it for at least 10 years (and evidence they have been doing it longer), but only now is the rest of the public seeing it. I have just enough statistics to see what they are doing, but it is complex enough that most people don't understand it.

[ Parent | on HN ]

Re:Valneva and Pfizer announce Phase 2 study for Lyme diseas... by incrudible on Thursday August 26, 2021 @09:51AM (#28314917)

It is a function of time. During the trials, it was a 95% reduction, Israel last reported a 39% reduction.

[ Parent | on HN ]

Re:Valneva and Pfizer announce Phase 2 study for Lyme diseas... by GrinningFool on Thursday August 26, 2021 @01:36PM (#28317944)

But that doesn't equate to saying that it is ineffective at preventing infection. I think we'd need follow-up studies showing a trend towards zero, but that doesn't seem to exist yet.

[ Parent | on HN ]